Metagenomics emerged in the late 1990s as a tool for accessing and studying the collective
microbial genetic material in the environment. The advent of the technology generated great …

Extremophiles are organisms that have evolved to exist in a variety of extreme
environments. They fall into a number of different classes that include thermophiles …

A gene encoding an esterase from Haloarcula marismortui, a halophilic archaeon from the
Dead Sea, was cloned, expressed in Escherichia coli, and the recombinant protein (Hm …

Metagenomics offers the possibility to screen for versatile biocatalysts. In this study, the
microbial community of the Sorghum bicolor rhizosphere was spiked with technical cashew …

We have studied the kinetics of hydrolysis of triacylglycerols, vinyl esters and p-nitrophenyl
butyrate by four carboxylesterases of the HSL family, namely recombinant human hormone …

Rv3487c (lipF), a member of the lipase family of Mycobacterium tuberculosis, is related to
virulence of this pathogen. Real-time RT-PCR analysis indicated that Rv3487c was induced …

Hormone-sensitive lipase (HSL) contributes importantly to the mobilization of fatty acids from
the triacylglycerols stored in adipocytes, which provide the main source of energy in …

Recent mutagenic and molecular modelling studies suggested a role for glycine 84 in the
putative oxyanion loop of the carboxylesterase EST2 from Alicyclobacillus acidocaldarius. A …

Serine hydrolase KIAA1363 is highly expressed in invasive cancer cells and is the major
protein in mouse brain diethylphosphorylated by and hydrolyzing low levels of chlorpyrifos …

Hormone-sensitive lipase (HSL) plays an important role in the regulation of rodent fat cell
lipolysis. It is regarded as an adipose tissue-specific enzyme whose sole metabolic role is …