Association of dipeptidylpeptidase 4 (CD26) with chondrocyte senescence and radiographic progression in knee osteoarthritis
Objective To evaluate the association of dipeptidylpeptidase 4 (DPP‐4; also known as
CD26) with cellular senescence of human cartilage and progression of knee osteoarthritis …
CD26) with cellular senescence of human cartilage and progression of knee osteoarthritis …
CBX4 deletion promotes tumorigenesis under KrasG12D background by inducing genomic instability
F Chen, W Hou, X Yu, J Wu, Z Li, J Xu, Z Deng… - … and Targeted Therapy, 2023 - nature.com
Abstract Chromobox protein homolog 4 (CBX4) is a component of the Polycomb group
(PcG) multiprotein Polycomb repressive complexes 1 (PRC1), which is participated in …
(PcG) multiprotein Polycomb repressive complexes 1 (PRC1), which is participated in …
Synergistic roles of CBX4 chromo and SIM domains in regulating senescence of primary human osteoarthritic chondrocytes
Background Cellular senescence is a critical factor contributing to osteoarthritis (OA).
Overexpression of chromobox homolog 4 (CBX4) in a mouse system was demonstrated to …
Overexpression of chromobox homolog 4 (CBX4) in a mouse system was demonstrated to …
Immune system-related plasma extracellular vesicles in healthy aging
Objectives To identify age-related plasma extracellular vehicle (EVs) phenotypes in healthy
adults. Methods EV proteomics by high-resolution mass spectrometry to evaluate EV protein …
adults. Methods EV proteomics by high-resolution mass spectrometry to evaluate EV protein …
Investigating the Function of Canonical Polycomb Repressive Complex 1 Phase Separation in Epigenetic Regulation
TA Oei - 2024 - dash.harvard.edu
Polycomb group (PcG) proteins are key developmental regulators involved in gene
repression and the maintenance of cell identity. They are a dynamic part of facultative …
repression and the maintenance of cell identity. They are a dynamic part of facultative …
Developing a Senomorphic Treatment Strategy in Osteoarthritis
YH Chen - 2022 - search.proquest.com
Osteoarthritis (OA) is the most common form of arthritis in the population worldwide, resulting
in significant disabilities. Currently, no treatments can prevent or reverse the development of …
in significant disabilities. Currently, no treatments can prevent or reverse the development of …