Heparin has been used extensively as an antithrombotic and anticoagulant for close to 100
years. This anticoagulant activity is attributed mainly to the pentasaccharide sequence …

Glycoscience assembles all the scientific disciplines involved in studying various molecules
and macromolecules containing carbohydrates and complex glycans. Such an ensemble …

Glycosaminoglycans (GAGs) are complex polysaccharides exhibiting a vast structural
diversity and fulfilling various functions mediated by thousands of interactions in the …

Recent biochemical, biophysical, and genetic studies have shown that heparan sulfate, a
major component of the cellular glycocalyx, participates in infection of SARS-CoV-2 by …

Viral variants of concern continue to arise for SARS-CoV-2, potentially impacting both
methods for detection and mechanisms of action. Here, we investigate the effect of an …

Inspired by the role of cell-surface glycoproteins as coreceptors for pathogens, we report the
development of GlycoGrip: a glycopolymer-based lateral flow assay for detecting SARS-CoV …

Natural glycosaminoglycans (GAGs) are informational molecules with astounding structural
diversity. Understanding the behavior of GAGs in the free and protein-bound states is critical …

Certain sulfated glycans, including those from marine sources, can show potential effects
against SARS-CoV-2. Here, a new fucosylated chondroitin sulfate (FucCS) from the sea …

Heparin (HP) and heparan sulfate (HS) are linear, anionically charged polysaccharides well-
known for their diverse biological activities. While HP is generally localized in mast cells and …

Complex carbohydrates (glycans) are the most abundant and versatile biopolymers in
nature. The broad diversity of biochemical functions that carbohydrates cover is a direct …