Introduction Macromolecular X-ray crystallography and cryo-EM are currently the primary
techniques used to determine the three-dimensional structures of proteins, nucleic acids …

Human serum albumin (HSA) is a multi-domain macromolecule with diverse ligand binding
capability because of its ability to allow allosteric modulation despite being a monomeric …

Identifying and characterizing metal-binding sites (MBS) within macromolecular structures is
imperative for elucidating their biological functions. CheckMyMetal (CMM) is a web based …

Human serum albumin (HSA) is the most abundant plasma protein, which functions to
transport a large range of ligands within the circulation. These interactions have important …

Zinc is required for virtually all biological processes. In plasma, Zn 2+ is predominantly
transported by human serum albumin (HSA), which possesses two Zn 2+-binding sites of …

In mammals, glycated serum albumin (gSA) contributes to the pathogenesis of many
metabolic diseases by activating the receptors (RAGE) for advanced glycation end products …

Two novel metal Schiff base complexes,[Co (L)(OH 2)(Cl)]. 2DMF (1) and [Ni (L)]. H 2 O (2)[H
2 L= N, N'-bis (5-bromo-3-(methoxy) salicylidene) cyclohexane-1, 2-diamine] were prepared …

In diabetes mellitus (DM) patients, the accumulation of advanced glycation end products
(AGE) leads to inflammation and oxidative stress through the activation of specific receptors …