Alopecia areata: a review of disease pathogenesis

F Rajabi, LA Drake, MM Senna… - British Journal of …, 2018 - academic.oup.com
Background Alopecia areata is a disorder that results in nonscarring hair loss. The
psychological impact can be significant, leading to feelings of depression and social …

Alopecia areata and the gut—the link opens up for novel therapeutic interventions

A Borde, A Åstrand - Expert opinion on therapeutic targets, 2018 - Taylor & Francis
Introduction: This review aims to raise the potential of the modern society's impact on gut
integrity often leading to increased intestinal permeability, as a cause or driver of Alopecia …

A randomized placebo-controlled single-center pilot study of the safety and efficacy of apremilast in subjects with moderate-to-severe alopecia areata

D Mikhaylov, A Pavel, C Yao, G Kimmel, J Nia… - Archives of …, 2019 - Springer
Alopecia areata (AA) is a common autoimmune disease that results in non-scarring hair
loss. AA pathogenesis is thought to involve multiple inflammatory cytokines. Apremilast is a …

A Potential Predictive Role of the Scalp Microbiome Profiling in Patients with Alopecia Areata: Staphylococcus caprae, Corynebacterium, and Cutibacterium Species

EJ Won, HH Jang, H Park, SJ Kim - Microorganisms, 2022 - mdpi.com
Little is known about the scalp bacterial composition of alopecia areata (AA) patients. The
aim of this study was to investigate the differences in the scalp microbiome of AA patients …

IL-17 inhibition: is it the long-awaited savior for alopecia areata?

Y Ramot, B Marzani, D Pinto, E Sorbellini… - Archives of …, 2018 - Springer
Abstract Interleukin-17 (IL-17) has been implicated in the pathogenesis of a large number of
inflammatory and autoimmune conditions, including skin disorders such as psoriasis …

Non-invasive targeted iontophoretic delivery of cetuximab to skin

M Lapteva, MA Sallam, A Goyon… - Expert opinion on …, 2020 - Taylor & Francis
Background: Cetuximab (CTX) is a glycosylated anti-EGFR monoclonal antibody of great
interest in the treatment of non-melanoma skin cancers. Its intravenous administration is …

Serum level of interleukin-15 in active alopecia areata patients and its relation to age, sex, and disease severity

M Ragab, E Hassan, D Niely… - Advances in Dermatology …, 2020 - termedia.pl
Serum level of interleukin-15 in active alopecia areata patients and its relation to age, sex,
and disease severity Page 1 Advances in Dermatology and Allergology 6, December/2020 …

Trichoscopy as an evaluation method for alopecia areata treatment: A comparative study

MM Fawzy, R Abdel Hay… - Journal of Cosmetic …, 2021 - Wiley Online Library
Background Trichoscopy is a useful tool for diagnosis and follow‐up of alopecia areata (AA)
patients. Both platelet‐rich plasma (PRP) and intralesional corticosteroids (ILCs) are …

The gut microbiome and Alopecia areata: Implications for early diagnostic biomarkers and novel therapies

Y Kang, Y Cai, Y Zhao, Y Yang - Frontiers in Nutrition, 2022 - frontiersin.org
Alopecia areata (AA) accounts for the autoimmune disorder mediated by T cells, whose
prognostic outcome cannot be predicted and curative treatment is unavailable at present …

What's new in the pathophysiology of alopecia areata? The possible contribution of skin and gut microbiome in the pathogenesis of alopecia–big opportunities, big …

K Migacz-Gruszka, W Branicki… - … Journal of Trichology, 2019 - journals.lww.com
The term “microbiome” defines the collective genome of all commensal, symbiotic, and
pathogenic microbes living in the human body. The composition of microbiota in the gut and …