The Role of Pax Genes in the Development of Tissues and Organs: Pax3 and Pax7 Regulate Muscle Progenitor Cell Functions
M Buckingham, F Relaix - Annu. Rev. Cell Dev. Biol., 2007 - annualreviews.org
Pax genes play key roles in the formation of tissues and organs during embryogenesis.
Pax3 and Pax7 mark myogenic progenitor cells and regulate their behavior and their entry …
Pax3 and Pax7 mark myogenic progenitor cells and regulate their behavior and their entry …
Pax genes: regulators of lineage specification and progenitor cell maintenance
JA Blake, MR Ziman - Development, 2014 - journals.biologists.com
Pax genes encode a family of transcription factors that orchestrate complex processes of
lineage determination in the developing embryo. Their key role is to specify and maintain …
lineage determination in the developing embryo. Their key role is to specify and maintain …
Reversing behavioural abnormalities in mice exposed to maternal inflammation
Viral infection during pregnancy is correlated with increased frequency of
neurodevelopmental disorders, and this is studied in mice prenatally subjected to maternal …
neurodevelopmental disorders, and this is studied in mice prenatally subjected to maternal …
The level of the transcription factor Pax6 is essential for controlling the balance between neural stem cell self-renewal and neurogenesis
Neural stem cell self-renewal, neurogenesis, and cell fate determination are processes that
control the generation of specific classes of neurons at the correct place and time. The …
control the generation of specific classes of neurons at the correct place and time. The …
Functional anthology of intrinsic disorder. 1. Biological processes and functions of proteins with long disordered regions
Identifying relationships between function, amino acid sequence, and protein structure
represents a major challenge. In this study, we propose a bioinformatics approach that …
represents a major challenge. In this study, we propose a bioinformatics approach that …
Trnp1 regulates expansion and folding of the mammalian cerebral cortex by control of radial glial fate
Evolution of the mammalian brain encompassed a remarkable increase in size of the
cerebral cortex, which includes tangential and radial expansion. However, the mechanisms …
cerebral cortex, which includes tangential and radial expansion. However, the mechanisms …
Neuronal fate determinants of adult olfactory bulb neurogenesis
MA Hack, A Saghatelyan, A de Chevigny, A Pfeifer… - Nature …, 2005 - nature.com
Adult neurogenesis in mammals is restricted to two small regions, including the olfactory
bulb, where GABAergic and dopaminergic interneurons are newly generated throughout the …
bulb, where GABAergic and dopaminergic interneurons are newly generated throughout the …
Transcription factors in glutamatergic neurogenesis: conserved programs in neocortex, cerebellum, and adult hippocampus
Glutamatergic, pyramidal-projection neurons are produced in the embryonic cerebral cortex
by a series of genetically programmed fate choices, implemented in large part by …
by a series of genetically programmed fate choices, implemented in large part by …
Concise review: Pax6 transcription factor contributes to both embryonic and adult neurogenesis as a multifunctional regulator
N Osumi, H Shinohara, K Numayama-Tsuruta… - Stem …, 2008 - academic.oup.com
Pax6 is a highly conserved transcription factor among vertebrates and is important in various
developmental processes in the central nervous system (CNS), including patterning of the …
developmental processes in the central nervous system (CNS), including patterning of the …
Pax6: a multi-level regulator of ocular development
O Shaham, Y Menuchin, C Farhy… - Progress in retinal and …, 2012 - Elsevier
Eye development has been a paradigm for the study of organogenesis, from the
demonstration of lens induction through epithelial tissue morphogenesis, to neuronal …
demonstration of lens induction through epithelial tissue morphogenesis, to neuronal …