Canada has long contended with harms arising from injection drug use. In response to
epidemics of HIV infection and overdose in Vancouver in the mid-1990s, a range of actors …

Background Hospital discharges against medical advice (AMA) is associated with negative
health outcomes and re-admissions. Patients with substance use disorders (SUD) are up to …

Mental Disorders, fifth edition (DSM-5). 1 The term “opioid” refers to any substance that acts
at opioid receptors, including prescription medications, such as morphine, and illicit drugs …

Background: Drug use–associated infective endocarditis (DUA-IE) is increasing as a result
of the opioid epidemic. Infective endocarditis may require valve surgery, but surgical …

Background Drug use is associated with increased morbidity and mortality but people who
use drugs experience significant barriers to care. Data are needed about the care …

Background Drug use is associated with increased morbidity and mortality but people who
use drugs experience significant barriers to care. Data are needed about the care …

We retrospectively evaluated off-label use of dalbavancin as secondary therapy in 32
patients with serious Staphylococcus aureus infections (endocarditis, osteomyelitis, septic …

Background People who use drugs (PWUD) frequent emergency departments at a higher
rate than the general population, and experience a greater frequency of soft tissue …

Objective Opioid withdrawal symptoms are widely understood to contribute to health risk but
have rarely been measured in community samples of opioid using people who inject drugs …

Background Hospitalizations related to opioid use disorder (OUD) are increasing,
necessitating an increase in the delivery of opioid agonist therapy (OAT) among hospitalized …