Association of vitamin D metabolism gene polymorphisms with autoimmunity: evidence in population genetic studies

AI Ruiz-Ballesteros, MR Meza-Meza… - International journal of …, 2020 - mdpi.com
A high prevalence of vitamin D (calcidiol) serum deficiency has been described in several
autoimmune diseases, including multiple sclerosis (MS), rheumatoid arthritis (AR), and …

Gene polymorphisms and biological effects of vitamin D receptor on nonalcoholic fatty liver disease development and progression

E Tourkochristou, A Mouzaki, C Triantos - International Journal of …, 2023 - mdpi.com
Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease, with
increasing prevalence worldwide. The genetic and molecular background of NAFLD …

Effects of vitamin D receptor gene polymorphisms on the prognosis of COVID‐19

T Apaydin, H Polat, C Dincer Yazan, C Ilgin… - Clinical …, 2022 - Wiley Online Library
Purpose Vitamin D deficiency has emerged as another potential risk factor for coronavirus
disease (COVID‐19) due to the immunomodulatory effects of 25 hydroxyvitamin D [25 (OH) …

[PDF][PDF] Advanced techniques and awaited clinical applications for human pluripotent stem cell differentiation into hepatocytes

E Luce, A Messina, JC Duclos‐Vallée… - …, 2021 - Wiley Online Library
Liver transplantation is currently the only curative treatment for several liver diseases such
as acute liver failure, end‐stage liver disorders, primary liver cancers, and certain genetic …

Vitamin D–VDR novel anti-inflammatory molecules—new insights into their effects on liver diseases

I Aggeletopoulou, K Thomopoulos, A Mouzaki… - International Journal of …, 2022 - mdpi.com
There is consistent evidence that vitamin D deficiency is strongly associated with liver
dysfunction, disease severity, and poor prognosis in patients with liver disease. Vitamin D …

VDR gene polymorphisms are associated with the increased susceptibility to COVID‐19 among iranian population: A case‐control study

A Jafarpoor, SM Jazayeri… - International Journal …, 2022 - Wiley Online Library
Abstract Coronavirus disease 2019 (COVID‐19) is an infectious disease caused by the
severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), but the pathogenesis is …

Role of FokI rs2228570 and Tru9I rs757343 polymorphisms in the mortality of patients infected with different variants of SARS-CoV-2

HRS Shawi, E Anvari, A Fateh - Archives of Medical Research, 2023 - Elsevier
Background and aim Low vitamin D levels are associated with the severity of coronavirus
disease 19 (COVID-19). Vitamin D receptor gene polymorphisms, such as Tru9I rs757343 …

Calcipotriol inhibits NLRP3 signal through YAP1 activation to alleviate cholestatic liver injury and fibrosis

X Wang, G Wang, J Qu, Z Yuan, R Pan… - Frontiers in …, 2020 - frontiersin.org
Cholestasis is common in multiple clinical circumstances. The NOD-like receptor protein 3
(NLRP3) inflammasome pathway has been demonstrated to play an important role in liver …

The influence of single nucleotide polymorphisms on vitamin D receptor protein levels and function in chronic liver disease

E Tourkochristou, EP Tsounis, H Tzoupis… - International Journal of …, 2023 - mdpi.com
Single nucleotide polymorphisms (SNPs) in the vitamin D receptor (VDR) gene have been
associated with chronic liver disease. We investigated the role of VDR SNPs on VDR protein …

Vitamin D receptor gene polymorphism and susceptibility to asthma: meta-analysis based on 17 case-control studies

MH Makoui, D Imani, M Motallebnezhad… - Annals of Allergy …, 2020 - Elsevier
Background During the last decade, several studies have evaluated the potential
association between vitamin D receptor (VDR) gene polymorphism and susceptibility to …