Transport phenomena in nanofluidics

RB Schoch, J Han, P Renaud - Reviews of modern physics, 2008 - APS
The transport of fluid in and around nanometer-sized objects with at least one characteristic
dimension below 100 nm enables the occurrence of phenomena that are impossible at …

Molecular sieving using nanofilters: past, present and future

J Han, J Fu, RB Schoch - Lab on a Chip, 2008 - pubs.rsc.org
Filtration of molecules by nanometer-sized structures is ubiquitous in our everyday life, but
our understanding of such molecular filtration processes is far less than desired. Until …

Nanofluidic devices and their applications

P Abgrall, NT Nguyen - Analytical chemistry, 2008 - ACS Publications
Recent developments in micro-and nanotechnologies made possible the fabrication of
devices integrating a deterministic network of nanochannels, ie, with at least one dimension …

Entropic trapping and escape of long DNA molecules at submicron size constriction

J Han, SW Turner, HG Craighead - Physical review letters, 1999 - APS
We studied the passage of DNA molecules, driven by an electric field, through a
microfabricated channel with 90 nm size constrictions. DNA molecules were entropically …

A patterned anisotropic nanofluidic sieving structure for continuous-flow separation of DNA and proteins

J Fu, RB Schoch, AL Stevens, SR Tannenbaum… - Nature …, 2007 - nature.com
Microfabricated regular sieving structures hold great promise as an alternative to gels to
improve the speed and resolution of biomolecule separation. In contrast to disordered …

Beyond gel electrophoresis: Microfluidic separations, fluorescence burst analysis, and DNA stretching

KD Dorfman, SB King, DW Olson, JDP Thomas… - Chemical …, 2013 - ACS Publications
This Review addresses methods for obtaining sequence information directly from
unamplified genomic length DNA. Our generic starting point is a large piece of DNA that …

Confinement-induced entropic recoil of single DNA molecules in a nanofluidic structure

SWP Turner, M Cabodi, HG Craighead - Physical review letters, 2002 - APS
The behavior of DNA molecules is observed in a nanofluidic device near the interface of two
regions that produce different configuration entropies. An electric field is applied to drive the …

DNA electrophoresis in microfabricated devices

KD Dorfman - Reviews of Modern Physics, 2010 - APS
Picking up at the conclusion of Viovy's review of the physics of gel electrophoresis [J.-L.
Viovy, Rev. Mod. Phys. 72, 813 (2000) 10.1103/RevModPhys. 72.813], this review …

Entropic trapping of macromolecules by mesoscopic periodic voids in a polymer hydrogel

L Liu, P Li, SA Asher - Nature, 1999 - nature.com
The separation of macromolecules such as polymers and DNA by means of electrophoresis,
gel permeation chromatography or filtration exploits size-dependent differences in the time it …

Modeling the separation of macromolecules: A review of current computer simulation methods

GW Slater, C Holm, MV Chubynsky… - …, 2009 - Wiley Online Library
Abstract Theory and numerical simulations play a major role in the development of improved
and novel separation methods. In some cases, computer simulations predict counterintuitive …