Recent advances in medicinal chemistry of oleanolic acid derivatives

YH Yang, SY Dai, FH Deng, LH Peng, C Li, YH Pei - Phytochemistry, 2022 - Elsevier
Oleanolic acid (OA), a ubiquitous pentacyclic oleanane-type triterpene isolated from edible
and medicinal plants, exhibits a wide spectrum of pharmacological activities and …

[HTML][HTML] Prophylactic and therapeutic roles of oleanolic acid and its derivatives in several diseases

A Sen - World Journal of Clinical Cases, 2020 - ncbi.nlm.nih.gov
Oleanolic acid (OA) and its derivatives are widely found in diverse plants and are naturally
effective pentacyclic triterpenoid compounds with broad prophylactic and therapeutic roles …

Evolving roles of natural terpenoids from traditional Chinese medicine in the treatment of osteoporosis

Y Zhuo, M Li, Q Jiang, H Ke, Q Liang… - Frontiers in …, 2022 - frontiersin.org
Osteoporosis (OP) is a systemic metabolic skeletal disease which can lead to reduction in
bone mass and increased risk of bone fracture due to the microstructural degradation …

Therapeutic potential of oleanolic acid in liver diseases

Y Wang, K Liu - Naunyn-Schmiedeberg's Archives of Pharmacology, 2024 - Springer
Liver-associated diseases affect millions of individuals worldwide. In developed countries,
the incidence of viral hepatitis is reducing due to advancements in disease prevention …

Fructus Ligustri Lucidi aqueous extract promotes calcium balance and short-chain fatty acids production in ovariectomized rats

B Chen, J Wei, R Zhu, H Zhang, B Xia, Y Liu… - Journal of …, 2021 - Elsevier
Abstract Ethnopharmacological relevance Fructus Ligustri Lucidi (FLL) is an edible herb with
anti-osteoporotic activity, yet whether and how the aqueous extract of this herb affect calcium …

Ursolic acid: biological functions and application in animal husbandry

G Liu, P Qin, X Cheng, L Wu, R Wang… - Frontiers in Veterinary …, 2023 - frontiersin.org
Ursolic acid (UA) is a plant-derived pentacyclic triterpenoid with 30 carbon atoms. UA has
anti-inflammatory, antioxidative, antimicrobial, hepato-protective, anticancer, and other …

Promotion of epithelial hyperplasia by interleukin‐8—CXCR axis in human prostate

DK Smith, SL Hasanali, J Wang, G Kallifatidis… - The …, 2020 - Wiley Online Library
Background The clinical manifestation of benign prostatic hyperplasia (BPH) is causally
linked to the inflammatory microenvironment and proliferation of epithelial and stromal cells …

A review of botany, phytochemistry, pharmacology, and applications of the herb with the homology of medicine and food: Ligustrum lucidum WT Aiton

L Chen, D Huang, L Jiang, J Yang, X Shi… - Frontiers in …, 2024 - frontiersin.org
Ligustrum lucidum WT Aiton is an outstanding herb with the homology of medicine and food.
Its ripe fruits are traditionally used as an important tonic for kidneys and liver in China …

Anti-Neuroinflammatory Effects and Mechanism of Action of Fructus ligustri lucidi Extract in BV2 Microglia

YJ Kim, SY Park, YJ Koh, JH Lee - Plants, 2021 - mdpi.com
For centuries, Fructus ligustri lucidi (FLL; the fruit of Ligustrum lucidum Aiton or Ligustrum
japonicum Thunb.) has been commonly used in traditional Chinese medicine for treating …

Integration WGCNA with LC-MS data for evaluating the processing status and transformation rules of Ligustri Lucidi Fructus: A novel strategy for evaluating the …

X Zhang, J Li, L Zhang, X Wu, Y Wang, L Zhang… - Talanta, 2025 - Elsevier
Abstract Ligustri Lucidi Fructus (LLF) is a traditional Chinese medicine (TCM) to treat
hepatopathy and osteopathy. Wine-processed LLF (WLLF) was much more widely used …