Epithelial–mesenchymal transition (EMT) and endothelial–mesenchymal transition (EndMT)
are physiological processes required for normal embryogenesis. However, these processes …

Abstract Runt-related transcription factor-1 (RUNX1), also known as acute myeloid
leukaemia 1 protein (AML1), is a member of the core-binding factor family of transcription …

The automobile tire antioxidant N-(1, 3-dimethylbutyl)-N'-phenyl-p-phenylenediamine
(6PPD) and its quinone metabolite 6PPDQ have recently received much attention for their …

Chromatin-associated RNA (caRNA) has been proposed as a type of epigenomic modifier.
Here, we test whether environmental stress can induce cellular dysfunction through …

Skin vasculature cross-talking with hair follicle stem cells (HFSCs) is poorly understood. Skin
vasculature undergoes dramatic remodeling during adult mouse hair cycle. Specifically, a …

Runt‐related transcription factor 1 (RUNX1) acts as a mediator of aberrant retinal
angiogenesis and has been implicated in the progression of proliferative diabetic …

Diabetic retinal disease (DRD), the most common complication of diabetes and a leading
cause of blindness in working age individuals, is now understood to be a form of sensory …

Background RUNX1 is a transcription factor and a master regulator for the specification of
the hematopoietic lineage during embryogenesis and postnatal megakaryopoiesis …

Loss of retinal blood flow autoregulation is an early feature of diabetes that precedes the
development of clinically recognizable diabetic retinopathy (DR). Retinal blood flow …

Neovascular eye diseases include conditions such as retinopathy of prematurity,
proliferative diabetic retinopathy, and neovascular age-related macular degeneration …