Chagas disease, caused by the protozoan Trypanosoma cruzi, is a lifelong and debilitating
illness of major significance throughout Latin America and an emergent threat to global …

Chagas disease is currently endemic to 21 Latin-American countries and has also become a
global concern because of globalization and mass migration of chronically infected …

The intestinal flora plays an important role in the development of many human and animal
diseases. Microbiome association studies revealed the potential regulatory function of …

Adaptive immunity controls Trypanosoma cruzi infection, but the protozoan parasite persists
and causes Chagas disease. T cells undergo apoptosis, and the efferocytosis of apoptotic …

Chagas disease (CD), caused by the protozoan Trypanosoma cruzi, is a prototypical
neglected tropical disease. Specific immunity promotes acute phase survival. Nevertheless …

Vaccines against parasites have lagged centuries behind those against viral and bacterial
infections, despite the devastating morbidity and widespread effects of parasitic diseases …

In mammals subverted as hosts by protozoan parasites, the latter and/or the agonists they
release are detected and processed by sensors displayed by many distinct immune cell …

During Trypanosoma cruzi infection, macrophages phagocytose parasites and remove
apoptotic cells through efferocytosis. While macrophage 1 (M1) produces proinflammatory …

The parasite Trypanosoma cruzi is the causative agent of Chagas disease, a potentially life-
threatening infection that represents a major health problem in Latin America. Several …

Many effects of the non-psychoactive cannabinoid, cannabidiol (CBD), have been described
in immune responses induced by strong immunological stimuli. It has also been shown that …