Quorum sensing interference by phenolic compounds–A matter of bacterial misunderstanding

EMF Lima, SC Winans, UM Pinto - Heliyon, 2023 - cell.com
Over the past decade, numerous publications have emerged in the literature focusing on the
inhibition of quorum sensing (QS) by plant extracts and phenolic compounds. However …

Functional and phylogenetic diversity of BSH and PVA enzymes

JW Daly, SJ Keely, CGM Gahan - Microorganisms, 2021 - mdpi.com
Bile salt hydrolase (BSH) and penicillin V acylase (PVA) are related enzymes that are
classified as choloylglycine hydrolases (CGH). BSH enzymes have attracted significant …

[HTML][HTML] Acylase enzymes disrupting quorum sensing alter the transcriptome and phenotype of Pseudomonas aeruginosa, and the composition of bacterial biofilms …

M De Celis, L Serrano-Aguirre, I Belda… - Science of the total …, 2021 - Elsevier
Biofilms represent an essential way of life and colonization of new environments for
microorganisms. This feature is regulated by quorum sensing (QS), a microbial …

Antagonistic activity of endophytic actinobacteria from native potatoes (Solanum tuberosum subsp. tuberosum L.) against Pectobacterium carotovorum subsp. carotovorum …

N Padilla-Gálvez, P Luengo-Uribe, S Mancilla… - BMC microbiology, 2021 - Springer
Abstract Background The native potatoes (Solanum tuberosum subsp. tuberosum L.) grown
in Chile (Chiloé) represent a new, unexplored source of endophytes to find potential …

Quorum‐quenching enzymes: Promising bioresources and their opportunities and challenges as alternative bacteriostatic agents in food industry

D Wang, F Cui, L Ren, J Li, T Li - Comprehensive Reviews in …, 2023 - Wiley Online Library
The problems of spoilage, disease, and biofilm caused by bacterial quorum‐sensing (QS)
systems have posed a significant challenge to the development of the food industry. Quorum …

Screening and Identification of a Streptomyces Strain with Quorum-Sensing Inhibitory Activity and Effect of the Crude Extracts on Virulence Factors of Pseudomonas …

Z Zhang, Y Sun, Y Yi, X Bai, L Zhu, J Zhu, M Gu, Y Zhu… - Microorganisms, 2023 - mdpi.com
Quorum-sensing (QS) is involved in numerous physiological processes in bacteria, such as
biofilm formation, sporulation, and virulence formation. Therefore, the search for new …

Enhancing the inhibition potential of AHL acylase PF2571 against food spoilage by remodeling its substrate scope via a computationally driven protein design

D Wang, F Cui, L Ren, X Tan, Q Li, J Li… - Journal of Agricultural …, 2022 - ACS Publications
The N-acyl homoserine lactone (AHL) acylases are widely used as quorum sensing (QS)
blockers to inhibit bacterial food spoilage. However, their substrate specificity for long-chain …

Novel Bifunctional Acylase from Actinoplanes utahensis: A Versatile Enzyme to Synthesize Antimicrobial Compounds and Use in Quorum Quenching Processes

L Serrano-Aguirre, R Velasco-Bucheli… - Antibiotics, 2021 - mdpi.com
Many intercellular communication processes, known as quorum sensing (QS), are regulated
by the autoinducers N-acyl-l-homoserine lactones (AHLs) in Gram-negative bacteria. The …

Penicillin G acylase-responsive near-infrared fluorescent probe: Unravelling biofilm regulation and combating bacterial infections

Y Liu, L Zhang, K Liu, LL Wu, HY Hu - Chinese Chemical Letters, 2024 - Elsevier
Antibiotic resistance poses a critical threat to human healthcare, largely driven by bacterial
biofilms. These biofilms resist the immune system and antibiotics, rendering enclosed …

Bioassay-Guided Fractionation Leads to the Detection of Cholic Acid Generated by the Rare Thalassomonas sp.

F Pheiffer, YKH Schneider, EH Hansen, JH Andersen… - Marine Drugs, 2022 - mdpi.com
Bacterial symbionts of marine invertebrates are rich sources of novel, pharmaceutically
relevant natural products that could become leads in combatting multidrug-resistant …