Decay happens: the role of active forgetting in memory

O Hardt, K Nader, L Nadel - Trends in cognitive sciences, 2013 - cell.com
Although the biological bases of forgetting remain obscure, the consensus among cognitive
psychologists emphasizes interference processes, rejecting decay in accounting for memory …

Reconsolidation: maintaining memory relevance

JLC Lee - Trends in neurosciences, 2009 - cell.com
The retrieval of a memory places it into a plastic state, the result of which is that the memory
can be disrupted or even enhanced by experimental treatment. This phenomenon has been …

Reconsolidation of memory: a decade of debate

A Besnard, J Caboche, S Laroche - Progress in neurobiology, 2012 - Elsevier
Memory consolidation refers to a slow process that stabilises a memory trace after initial
acquisition of novel events. The consolidation theory posits that once a memory is stored in …

The role of metaplasticity mechanisms in regulating memory destabilization and reconsolidation

PSB Finnie, K Nader - Neuroscience & Biobehavioral Reviews, 2012 - Elsevier
Memory allows organisms to predict future events based on prior experiences. This requires
encoded information to persist once important predictors are extracted, while also being …

Double dissociation of the requirement for GluN2B-and GluN2A-containing NMDA receptors in the destabilization and restabilization of a reconsolidating memory

AL Milton, E Merlo, P Ratano, BL Gregory… - Journal of …, 2013 - Soc Neuroscience
Signaling at NMDA receptors (NMDARs) is known to be important for memory
reconsolidation, but while most studies show that NMDAR antagonists prevent memory …

Intra-amygdala and systemic antagonism of NMDA receptors prevents the reconsolidation of drug-associated memory and impairs subsequently both novel and …

AL Milton, JLC Lee, VJ Butler, R Gardner… - Journal of …, 2008 - Soc Neuroscience
The amygdala has long been considered a primary locus in mediating the effects of
previously drug-associated stimuli on subsequent drug-seeking behavior, and the NMDA …

Disrupting astrocyte–neuron lactate transfer persistently reduces conditioned responses to cocaine

B Boury-Jamot, A Carrard, JL Martin, O Halfon… - Molecular …, 2016 - nature.com
A central problem in the treatment of drug addiction is the high risk of relapse often
precipitated by drug-associated cues. The transfer of glycogen-derived lactate from …

Older and stronger object memories are selectively destabilized by reactivation in the presence of new information

BD Winters, MC Tucci… - Learning & memory, 2009 - learnmem.cshlp.org
Reactivation can destabilize previously consolidated memories, rendering them vulnerable
to disruption and necessitating a process of reconsolidation in order for them to be …

Reconsolidation of drug memories

BA Sorg - Neuroscience & Biobehavioral Reviews, 2012 - Elsevier
Persistent, unwanted memories are believed to be key contributors to drug addiction and the
chronic relapse problem over the lifetime of the addict. Contrary to the long-held idea that …

Behavioural memory reconsolidation of food and fear memories

CR Flavell, DJ Barber, JLC Lee - Nature communications, 2011 - nature.com
The reactivation of a memory through retrieval can render it subject to disruption or
modification through the process of memory reconsolidation. In both humans and rodents …