Anagen stage hair follicles (HFs) exhibit “immune privilege (IP)” from the level of the bulge
downwards to the bulb. Both passive and active IP mechanisms protect HFs from …

The most common cause of acquired thyroid dysfunction is autoimmune thyroid disease,
which is an organ-specific autoimmune disease with two presentation phenotypes …

The endocannabinoid system (ECS) has lately been proven to be an important, multifaceted
homeostatic regulator, which influences a wide-variety of physiological processes all over …

PTPN22 encodes a tyrosine phosphatase that is expressed by haematopoietic cells and
functions as a key regulator of immune homeostasis by inhibiting T-cell receptor signalling …

Inheritance of a coding variant of the protein tyrosine phosphatase nonreceptor type 22
(PTPN22) gene is associated with increased susceptibility to autoimmunity and infection …

Background Rheumatoid arthritis (RA) is classified as seropositive or seronegative,
depending on the presence/absence of rheumatoid factor (RF), primarily IgM RF, and/or anti …

Rheumatoid arthritis (RA) is a common inflammatory disease in which both genetic and
environmental factors play a role in disease development. Based on twin studies, the …

The incidence of autoimmune diseases is increasing worldwide, thus stimulating studies on
their etiopathogenesis, derived from a complex interaction between genetic and …

Background Psoriasis is a chronic inflammatory autoimmune skin disorder. Several studies
suggested psoriasis to be a complex multifactorial disease, but the exact triggering factor is …

Myasthenia Gravis (MG) is a paradigm of organ-specific autoimmune disease (AID). It is
mediated by antibodies that target the neuromuscular junction. The purpose of this review is …