[HTML][HTML] Versatile signaling mechanisms of inositol pyrophosphates

MN Trung, D Furkert, D Fiedler - Current opinion in chemical biology, 2022 - Elsevier
Inositol pyrophosphates (PP-InsPs) constitute a group of highly charged messengers, which
regulate central biological processes in health and disease, such as cellular phosphate and …

Kcs1 and Vip1: The Key Enzymes behind Inositol Pyrophosphate Signaling in Saccharomyces cerevisiae

LI Gogianu, LL Ruta, IC Farcasanu - Biomolecules, 2024 - mdpi.com
The inositol pyrophosphate pathway, a complex cell signaling network, plays a pivotal role
in orchestrating vital cellular processes in the budding yeast, where it regulates cell cycle …

DNA damage-induced autophagy is regulated by inositol polyphosphate synthetases in Candida albicans

J Du, Y Dong, H Zhu, Y Deng, C Sa, Q Yu… - Biochimica et Biophysica …, 2024 - Elsevier
DNA damage-induced autophagy is a new type of autophagy that differs from traditional
macroautophagy; however, this type of autophagy has not been identified in the pathogenic …

Arg1 from Cryptococcus neoformans lacks PI3 kinase activity and conveys virulence roles via its IP3-4 kinase activity

D Desmarini, G Liu, H Jessen, B Bowring, A Connolly… - mBio, 2024 - Am Soc Microbiol
Inositol tris/tetrakis phosphate kinases (IP3-4K) in the human fungal priority pathogens,
Cryptococcus neoformans (Cn Arg1) and Candida albicans (Ca Ipk2), convey numerous …

TNP Analogues Inhibit the Virulence Promoting IP3-4 Kinase Arg1 in the Fungal Pathogen Cryptococcus neoformans

D Desmarini, D Truong, L Wilkinson-White… - Biomolecules, 2022 - mdpi.com
New antifungals with unique modes of action are urgently needed to treat the increasing
global burden of invasive fungal infections. The fungal inositol polyphosphate kinase (IPK) …

Plasma Membrane Phosphatidylinositol 4-Phosphate Is Necessary for Virulence of Candida albicans

JB Konopka - Mbio, 2022 - Am Soc Microbiol
Phosphatidylinositol lipids regulate key processes, including vesicle trafficking and cell
polarity. A recent study identified novel roles for phosphatidylinositol 4-phosphate (PI4P) in …

СИНТЕЗ ИНОЗИТОЛФОСФАТОВ В КОРНЯХ ПРОРОСТКОВ ГОРОХА PISUM SATIVUM L. НА РАННИХ ЭТАПАХ ПОСЛЕ ИНОКУЛЯЦИИ RHIZOBIUM …

АД БОВИН, СА ШИРОБОКОВА… - … Учредители: ООО" Эко …, 2023 - elibrary.ru
Изучение участия инозитолфосфатов в регуляции сигнального обмена между
бобовыми растениями и клубеньковыми бактериями, представляет большой интерес …

[HTML][HTML] Inositol phosphates' synthesis in pea Pisum sativum L. root seedlings at the early stages after Rhizobium leguminosarum bv. viciae inoculation

AD Bovin, SA Shirobokova… - Ecological …, 2023 - journals.eco-vector.com
Studying the role of inositol phosphates in the regulation of signal exchange between
leguminous plants and nodule bacteria is of great interest since it affects the regulation of …