Fetal growth restriction and related placental pathologies such as preeclampsia, stillbirth,
and placental abruption are believed to arise in early pregnancy when inadequate …

The concept of gene therapy arose during the 1960s and early 1970s. Rogers and Pfuderer
1 carried out the first genetic modification of a virus (Tobacco mosaic virus [TMV]), and …

Abstract The BMP/TGFβ-Smad, Notch and VEGF signaling guides formation of endothelial
tip and stalk cells. However, the crosstalk of bone morphogenetic proteins (BMPs) and …

We evaluated late effects of AdhAQP1 administration in five subjects in a clinical trial for
radiation-induced salivary hypofunction (http://www. clinicaltrials. gov/ct/show …

Abstract microRNAs comprise a novel class of endogenous small non-coding RNAs that
have been shown to be implicated in both vascular damage and bone pathophysiology …

Recent progress in lymphatic vessel biology and in novel imaging techniques has
established the importance of the lymphatic vasculature as part of the cardiovascular …

The mammalian circulatory system comprises both the cardiovascular system and the
lymphatic system. In contrast to the closed, high-pressure and circular blood vascular …

Cardiovascular disease is the leading cause of morbidity and mortality in developed
countries. Stroke is associated with a marked disability burden and has a major economic …

Foetal growth restriction (FGR) and associated placental pathologies such as pre-eclampsia
and stillbirth arise in early pregnancy when inadequate remodelling of maternal spiral …

Gene therapy has the potential to serve as an adaptable platform technology for treating
various diseases. Cardiovascular disease is a major cause of mortality in the developed …