Update on Chlamydia trachomatis vaccinology

LM de la Maza, G Zhong… - Clinical and Vaccine …, 2017 - Am Soc Microbiol
Attempts to produce a vaccine to protect against Chlamydia trachomatis-induced trachoma
were initiated more than 100 years ago and continued for several decades. Using whole …

Chlamydia trachomatis vaccines for genital infections: where are we and how far is there to go?

LM de la Maza, TL Darville, S Pal - Expert review of vaccines, 2021 - Taylor & Francis
Introduction Chlamydia trachomatis is the most common sexually transmitted bacterial
pathogen in the world. Antibiotic treatment does not prevent against reinfection and a …

Efficacy of a synthetic peptide Chlamydia pecorum major outer membrane protein vaccine in a wild koala (Phascolarctos cinereus) population

SJ Simpson, DP Higgins, P Timms, VSA Mella… - Scientific Reports, 2023 - nature.com
Chlamydiosis is a significant disease affecting Eastern Australian koala (Phascolarctos
cinereus) populations, impacting individual animal welfare and fecundity and therefore …

Advances in vaccine development for Chlamydia trachomatis

TB Poston - Pathogens and Disease, 2024 - academic.oup.com
Chlamydia trachomatis is the most prevalent bacterial sexually transmitted infection globally.
Antibiotic treatment is highly effective, but infection is often asymptomatic resulting in most …

A systematic review: the role of resident memory T cells in infectious diseases and their relevance for vaccine development

V Muruganandah, HD Sathkumara, S Navarro… - Frontiers in …, 2018 - frontiersin.org
Background Resident memory T cells have emerged as key players in the immune response
generated against a number of pathogens. Their ability to take residence in non-lymphoid …

[HTML][HTML] Detection of chlamydia infection within human testicular biopsies

ER Bryan, RI McLachlan, L Rombauts… - Human …, 2019 - academic.oup.com
Male chlamydial infection has been understudied despite male and female infections
occurring at similar rates. This is particularly true of asymptomatic infections, which occur in …

Zika virus in the male reproductive tract

L Stassen, CW Armitage, DJ Van der Heide… - Viruses, 2018 - mdpi.com
Arthropod-borne viruses (arboviruses) are resurging across the globe. Zika virus (ZIKV) has
caused significant concern in recent years because it can lead to congenital malformations …

Chlamydia trachomatis vaccine development – a view on the current challenges and how to move forward

ÁH Borges, F Follmann, J Dietrich - Expert Review of Vaccines, 2022 - Taylor & Francis
Introduction Chlamydia trachomatis is the most common sexually transmitted bacterial
pathogen in the world. A licensed vaccine is not yet available, but the first vaccines have …

Multi-component prime-boost Chlamydia trachomatis vaccination regimes induce antibody and T cell responses and accelerate clearance of infection in a non …

E Lorenzen, V Contreras, AW Olsen… - Frontiers in …, 2022 - frontiersin.org
It is of international priority to develop a vaccine against sexually transmitted Chlamydia
trachomatis infections to combat the continued global spread of the infection. The optimal …

A Chlamydia trachomatis VD1-MOMP vaccine elicits cross-neutralizing and protective antibodies against C/C-related complex serovars

AW Olsen, I Rosenkrands, MJ Holland, P Andersen… - npj Vaccines, 2021 - nature.com
Ocular and urogenital infections with Chlamydia trachomatis (Ct.) are caused by a range of
different serovars. The first Ct. vaccine in clinical development (CTH522/CAF® 01) induced …