Roles and crosstalks of macrophages in diabetic nephropathy

HD Li, YK You, BY Shao, WF Wu, YF Wang… - Frontiers in …, 2022 - frontiersin.org
Diabetic nephropathy (DN) is the most common chronic kidney disease. Accumulation of
glucose and metabolites activates resident macrophages in kidneys. Resident macrophages …

The effect of sodium-glucose cotransporter 2 inhibitors on biomarkers of inflammation: A systematic review and meta-analysis of randomized controlled trials

D Wang, J Liu, L Zhong, S Li, L Zhou… - Frontiers in …, 2022 - frontiersin.org
Aims: Inflammatory biomarkers may play vital roles in the pathophysiology of diabetes and
diabetic cardiorenal complications. Sodium-glucose cotransporter-2 (SGLT2) inhibitors have …

Time restricted feeding decreases renal innate immune cells and blood pressure in hypertensive mice

BM Sims, BL Goodlett, ML Allbee, EJ Pickup… - Journal of …, 2022 - journals.lww.com
Background: Renal innate immune cell accumulation and inflammation are associated with
hypertension. Time restricted feeding (TRF) has been reported to decrease inflammation …

The regulatory effect of intermittent fasting on inflammasome activation in health and disease

C Wang, Z Liu, J Cai, X Xu - Nutrition Reviews, 2024 - academic.oup.com
Intermittent fasting (IF), one of the most popular diets, can regulate inflammation and
promote health; however, the detailed molecular mechanisms are not fully understood. The …

A 5: 2 Intermittent Fasting Meal Replacement Diet and Glycemic Control for Adults With Diabetes: The EARLY Randomized Clinical Trial

L Guo, Y Xi, W Jin, H Yuan, G Qin, S Chen… - JAMA Network …, 2024 - jamanetwork.com
Importance An intermittent fasting plan consisting of 2 nonconsecutive fasting days and 5
days of habitual intake per week and meal replacement diet (5: 2 MR) could provide …

EGCG alleviates Ochratoxin A-induced pyroptosis in rat's kidney by inhibiting NLRP3/Caspase-1/GSDMD signaling pathway

I Bozkurt, Z Halici, EB Zirh… - Food and Chemical …, 2024 - Elsevier
Ochratoxin A (OTA) exposure is inevitable due to its contamination in foods, and there is no
treatment for the OTA induced organ toxicity. We evaluate the effect of epigallocatechin …

Effects of idebenone and coenzyme Q10 on NLRP3/caspase-1/IL-1β pathway regulation on ethanol-induced hepatotoxicity in rats

FB Yoladi, SS Palabiyik-Yucelik… - Drug and Chemical …, 2024 - Taylor & Francis
Chronic and excessive alcohol consumption leads to liver toxicity. There is a need to
investigate effective therapeutic strategies to alleviate alcohol-induced liver injury, which …

Histopathological Changes In Lung Tissue Caused By Diabetes: A Review

AB Yıldırım, D Karabulut, E Kaymak… - Journal of Basic and …, 2023 - dergipark.org.tr
Diabetes mellitus associated with oxidative stress and inflammation can affect many organs.
While the effects of diabetes on many organs are well known and documented, its …

[HTML][HTML] Role of NLRP3 Inflammasomes in Neurodegenerative Diseases

N Demirtas, B Sahin-Mazlumoglu… - The Eurasian Journal …, 2023 - ncbi.nlm.nih.gov
Large-scale neuronal degeneration in the human brain is a hallmark of neurodegenerative
diseases. These diseases range in location and cause, but they all have neurodegenerative …

[HTML][HTML] Experimental Approaches to Diabetes Mellitus

M Yayla, D Binnetoğlu - The Eurasian Journal of Medicine, 2022 - ncbi.nlm.nih.gov
One of the most common health problems today, diabetes is a serious, chronic, and complex
disease characterized by high blood glucose levels. Nowadays, experimental diabetes …