Transport of drugs from blood vessels to tumour tissue
MW Dewhirst, TW Secomb - Nature Reviews Cancer, 2017 - nature.com
The effectiveness of anticancer drugs in treating a solid tumour is dependent on delivery of
the drug to virtually all cancer cells in the tumour. The distribution of drug in tumour tissue …
the drug to virtually all cancer cells in the tumour. The distribution of drug in tumour tissue …
Predicting and monitoring cancer treatment response with diffusion‐weighted MRI
An imaging biomarker that would provide for an early quantitative metric of clinical treatment
response in cancer patients would provide for a paradigm shift in cancer care. Currently …
response in cancer patients would provide for a paradigm shift in cancer care. Currently …
Diffusion-weighted magnetic resonance imaging for predicting and detecting early response to chemoradiation therapy of squamous cell carcinomas of the head and …
S Kim, L Loevner, H Quon, E Sherman… - Clinical Cancer …, 2009 - AACR
Purpose: The aim of this study was to investigate the utility of apparent diffusion coefficient
(ADC) for prediction and early detection of treatment response in head and neck squamous …
(ADC) for prediction and early detection of treatment response in head and neck squamous …
Diffusion-weighted imaging of the breast: principles and clinical applications
R Woodhams, S Ramadan, P Stanwell, S Sakamoto… - Radiographics, 2011 - pubs.rsna.org
Diffusion-weighted imaging provides a novel contrast mechanism in magnetic resonance
(MR) imaging and has a high sensitivity in the detection of changes in the local biologic …
(MR) imaging and has a high sensitivity in the detection of changes in the local biologic …
[HTML][HTML] Functional diffusion map as an early imaging biomarker for high-grade glioma: correlation with conventional radiologic response and overall survival
DA Hamstra, CJ Galbán, CR Meyer… - Journal of clinical …, 2008 - ncbi.nlm.nih.gov
Purpose Assessment of radiologic response (RR) for brain tumors utilizes the Macdonald
criteria 8 to 10 weeks from the start of treatment. Diffusion magnetic resonance imaging …
criteria 8 to 10 weeks from the start of treatment. Diffusion magnetic resonance imaging …
Diffusion-weighted magnetic resonance imaging in the early detection of response to chemoradiation in cervical cancer
VN Harry, SI Semple, FJ Gilbert, DE Parkin - Gynecologic oncology, 2008 - Elsevier
OBJECTIVE: To investigate diffusion-weighted magnetic resonance imaging (DWI) as an
early and reproducible response indicator in women receiving concurrent radiotherapy and …
early and reproducible response indicator in women receiving concurrent radiotherapy and …
Non–small cell lung cancer: detection of early response to chemotherapy by using contrast-enhanced dynamic and diffusion-weighted MR imaging
H Yabuuchi, M Hatakenaka, K Takayama, Y Matsuo… - Radiology, 2011 - pubs.rsna.org
Purpose To evaluate the ability of dynamic contrast material–enhanced and diffusion-
weighted (DW) magnetic resonance (MR) imaging to help detect early response to …
weighted (DW) magnetic resonance (MR) imaging to help detect early response to …
Predicting Pathologic Response to Neoadjuvant Chemotherapy in Breast Cancer by Using MR Imaging and Quantitative 1H MR Spectroscopy1
Purpose: To compare changes in the concentration of choline-containing compounds (tCho)
and in tumor size at follow-up after neoadjuvant chemotherapy (NAC) between patients who …
and in tumor size at follow-up after neoadjuvant chemotherapy (NAC) between patients who …
Immunochemotherapy with intensive consolidation for primary CNS lymphoma: a pilot study and prognostic assessment by diffusion-weighted MRI
MJ Wieduwilt, F Valles, S Issa, CM Behler… - Clinical Cancer …, 2012 - AACR
Purpose: We evaluated a novel therapy for primary central nervous system lymphoma
(PCNSL) with induction immunochemotherapy with high-dose methotrexate, temozolomide …
(PCNSL) with induction immunochemotherapy with high-dose methotrexate, temozolomide …
Apparent diffusion coefficient modifications in assessing gastro-oesophageal cancer response to neoadjuvant treatment: comparison with tumour regression grade at …
Objectives To assess changes in apparent diffusion coefficient (ΔADC) and volume (ΔV)
after neoadjuvant treatment (NT), and tumour regression grade (TRG) in gastro …
after neoadjuvant treatment (NT), and tumour regression grade (TRG) in gastro …