The alphaviruses are a genus of 26 enveloped viruses that cause disease in humans and
domestic animals. Mosquitoes or other hematophagous arthropods serve as vectors for …

The ongoing COVID-19 pandemic, periodic recurrence of viral infections, and the
emergence of challenging variants has created an urgent need of alternative therapeutic …

Autophagy influences numerous cellular processes, including innate and adaptive immunity
against intracellular pathogens. However, some viruses, including dengue virus (DENV) …

Positive-strand RNA virus genome replication is invariably associated with extensively
rearranged intracellular membranes. Recent biochemical and electron microscopy …

Publisher Summary It is clear from the experimental data that there are some similarities in
RNA replication for all eukaryotic positive-stranded RNA viruses—that is, the mechanism of …

It is urgent to develop disease models to dissect mechanisms regulating severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Here, we derive airway …

All single‐stranded 'positive‐sense'RNA viruses that infect mammalian, insect or plant cells
rearrange internal cellular membranes to provide an environment facilitating virus …

Many viruses reorganise cellular membrane compartments and the cytoskeleton to generate
subcellular microenvironments called virus factories or 'viroplasm'. These create a platform …

Publisher Summary Animal viruses permeabilize cells at two well-defined moments during
infection:(1) early, when the virus gains access to the cytoplasm, and (2) during the …

▪ Abstract The replication of positive-strand RNA viruses is a complex multi-step process
involving interactions between the viral genome, virus-encoded replication factors, and host …