Cross-classification clustering: An efficient multi-object tracking technique for 3-d instance segmentation in connectomics

Y Meirovitch, L Mi, H Saribekyan… - Proceedings of the …, 2019 - openaccess.thecvf.com
Pixel-accurate tracking of objects is a key element in many computer vision applications,
often solved by iterated individual object tracking or instance segmentation followed by …

DotMotif: an open-source tool for connectome subgraph isomorphism search and graph queries

JK Matelsky, EP Reilly, EC Johnson, J Stiso… - Scientific Reports, 2021 - nature.com
Recent advances in neuroscience have enabled the exploration of brain structure at the
level of individual synaptic connections. These connectomics datasets continue to grow in …

Igneous: Distributed dense 3D segmentation meshing, neuron skeletonization, and hierarchical downsampling

W Silversmith, A Zlateski, JA Bae, I Tartavull… - Frontiers in neural …, 2022 - frontiersin.org
Three-dimensional electron microscopy images of brain tissue and their dense
segmentations are now petascale and growing. These volumes require the mass production …

CONFIRMS: a toolkit for scalable, black box connectome assessment and investigation

C Bishop, J Matelsky, M Wilt, J Downs… - 2021 43rd Annual …, 2021 - ieeexplore.ieee.org
The nanoscale connectomics community has recently generated automated and semi-
automated" wiring diagrams" of brain subregions from terabytes and petabytes of dense 3D …

Synapse-aware skeleton generation for neural circuits

B Matejek, D Wei, X Wang, J Zhao, K Palágyi… - … Image Computing and …, 2019 - Springer
Reconstructed terabyte and petabyte electron microscopy image volumes contain fully-
segmented neurons at resolutions fine enough to identify every synaptic connection. After …

Circuit motifs and graph properties of connectome development in C. elegans

JK Matelsky, R Norman-Tenazas, F Davenport… - bioRxiv, 2021 - biorxiv.org
Network science is a powerful tool that can be used to better explore the complex structure
of brain networks. Leveraging graph and motif analysis tools, we interrogate C. elegans …

Intra-and Inter-Cellular Awareness for 3D Neuron Tracking and Segmentation in Large-Scale Connectomics

H Zhai, J Liu, B Hong, J Liu, Q Xie… - Medical Imaging with …, 2024 - openreview.net
Currently, most state-of-the-art pipelines for 3D micro-connectomic reconstruction deal with
neuron over-segmentation, agglomeration and subcellular compartment (nuclei …

Scalable Biologically-Aware Skeleton Generation for Connectomic Volumes

B Matejek, T Franzmeyer, D Wei… - IEEE transactions on …, 2022 - ieeexplore.ieee.org
As connectomic datasets exceed hundreds of terabytes in size, accurate and efficient
skeleton generation of the label volumes has evolved into a critical component of the …

Transfer learning analysis of image processing workflows for electron microscopy datasets

EC Johnson, LM Rodriguez… - 2019 53rd Asilomar …, 2019 - ieeexplore.ieee.org
Neuroscientists are collecting Electron Microscopy (EM) datasets at increasingly faster rates.
This modality offers an unprecedented map of brain structure at the resolution of individual …

Connecting neural reconstruction integrity (NRI) to graph metrics and biological priors

EP Reilly, EC Johnson, MJ Hughes… - Complex Networks XI …, 2020 - Springer
We previously introduced the Neural Reconstruction Integrity (NRI) metric as a measure of
how well the connectivity of the brain is measured in a neural circuit reconstruction, which …