Biochemical Functions of Coenzyme Q10

FL Crane - Journal of the American College of Nutrition, 2001 - Taylor & Francis
Coenzyme Q is well defined as a crucial component of the oxidative phosphorylation
process in mitochondria which converts the energy in carbohydrates and fatty acids into ATP …

Acid and neutral sphingomyelinases: roles and mechanisms of regulation

N Marchesini, YA Hannun - Biochemistry and cell biology, 2004 - cdnsciencepub.com
La céramide, un nouveau second messager et lipide bioactif, est principalement formée lors
de l'hydrolyse de la sphingomyéline par des sphingomyélinases. Au moins deux …

Ceramide in apoptosis signaling: relationship with oxidative stress

N Andrieu-Abadie, V Gouazé, R Salvayre… - Free Radical Biology and …, 2001 - Elsevier
Ceramide is one of the major sphingosine-based lipid second messengers that is generated
in response to various extracellular agents. However, while widespread attention has …

Coenzyme Q10 affects expression of genes involved in cell signalling, metabolism and transport in human CaCo-2 cells

DA Groneberg, B Kindermann, M Althammer… - The international journal …, 2005 - Elsevier
Coenzyme Q10 is an essential cofactor in the electron transport chain and serves as an
important antioxidant in both mitochondria and lipid membranes. CoQ10 is also an …

Sphingolipids and mitochondrial apoptosis

GA Patwardhan, LJ Beverly, LJ Siskind - Journal of bioenergetics and …, 2016 - Springer
The sphingolipid family of lipids modulate several cellular processes, including proliferation,
cell cycle regulation, inflammatory signaling pathways, and cell death. Several members of …

Sphingomyelin hydrolysis during apoptosis

N Andrieu-Abadie, T Levade - … et Biophysica Acta (BBA)-Molecular and Cell …, 2002 - Elsevier
Sphingolipid breakdown products are now being recognized as important players in
apoptosis. Ceramide, which is considered to serve as second messenger, is mainly …

Is coenzyme Q a key factor in aging?

G López-Lluch, JC Rodríguez-Aguilera… - Mechanisms of ageing …, 2010 - Elsevier
Coenzyme Q (Q) is a key component for bioenergetics and antioxidant protection in the cell.
During the last years, research on diseases linked to Q-deficiency has highlighted the …

Coenzyme Q and its role in the dietary therapy against aging

A Varela-López, F Giampieri, M Battino, JL Quiles - Molecules, 2016 - mdpi.com
Coenzyme Q (CoQ) is a naturally occurring molecule located in the hydrophobic domain of
the phospholipid bilayer of all biological membranes. Shortly after being discovered, it was …

The multiple roles of coenzyme Q in cellular homeostasis and their relevance for the pathogenesis of coenzyme Q deficiency

E Baschiera, U Sorrentino, C Calderan… - Free Radical Biology …, 2021 - Elsevier
Coenzyme Q (CoQ) is a redox active lipid that plays a central role in cellular homeostasis. It
was discovered more than 60 years ago because of its role as electron transporter in the …

[HTML][HTML] The plasma lipidome in acute myeloid leukemia at diagnosis in relation to clinical disease features

T Pabst, L Kortz, GM Fiedler, U Ceglarek, JR Idle… - BBA clinical, 2017 - Elsevier
Background Early studies established that certain lipids were lower in acute myeloid
leukemia (AML) cells than normal leukocytes. Because lipids are now known to play an …