Recent advances have revealed common pathological changes in neurodegenerative
diseases, such as Alzheimer's disease, Parkinson's disease and amyotrophic lateral …

The introduction of high-resolution time lapse imaging and molecular biological tools has
changed dramatically the rate of progress towards the understanding of the complex …

The sigma-1 receptor (Sig-1R) is an endoplasmic reticulum (ER) protein that resides
specifically in the mitochondria-associated endoplasmic reticulum (ER) membrane (MAM) …

Schizophrenia is a neurodevelopmental disorder whose clinical features include
impairments in perception, cognition and motivation. These impairments reflect alterations in …

Sigma-1 receptor (S1R) is a multi-functional, ligand-operated protein situated in
endoplasmic reticulum (ER) membranes and changes in its function and/or expression have …

This report provides a historical overview of research concerning the endogenous
hallucinogen N, N-dimethyltryptamine (DMT), focusing on data regarding its biosynthesis …

Abstract N, N-dimethyltryptamine (DMT) is an indole alkaloid widely found in plants and
animals. It is best known for producing brief and intense psychedelic effects when ingested …

Inter-organelle signaling plays important roles in many physiological functions. Endoplasmic
reticulum (ER)–mitochondrion signaling affects intramitochondrial calcium (Ca 2+) …

The membrane of the endoplasmic reticulum (ER) of a cell forms contacts directly with
mitochondria whereby the contact is referred to as the m itochondrion-a ssociated ER m …

Background Although depression is the leading cause of disability worldwide, its
pathophysiology is poorly understood. Recent evidence has suggested that sirtuins (SIRTs) …