Monocytes circulate the vasculature at steady state and are recruited to sites of inflammation
where they differentiate into macrophages (MФ) to replenish tissue-resident MФ populations …

Simple Summary Bisphenol A (BPA) is primarily used to produce polycarbonate plastics,
such as water bottles. Exposure to BPA has been shown to increase the growth of breast …

Diverse mouse strains have different health and life spans, mimicking the diversity among
humans. To capture conserved aging signatures, we studied long‐lived C57BL/6J and short …

ABSTRACT A preliminary study investigating immunotherapy strategies for aggressive triple
negative breast cancer (TNBC) revealed an overexpression of genes involved in the release …

Rhinovirus (RV) and respiratory syncytial virus (RSV) are common causes of bronchiolitis.
Unlike an RSV etiology, an RV etiology is associated with a markedly increased risk of …

Inflammation can trigger lasting phenotypes in immune and non-immune cells. Whether and
how human infections and associated inflammation can form innate immune memory in …

Abstract scRNA-seq datasets are increasingly used to identify gene panels that can be
probed using alternative technologies, such as spatial transcriptomics, where choosing the …

SARS-CoV-2, the virus that causes COVID-19, has given rise to one of the largest
pandemics, affecting millions worldwide. High neutrophil-to-lymphocyte ratios have been …

Viral antigens can activate phagocytes, inducing inflammation, but the mechanisms are
barely explored. The aim of this study is to investigate how viral oligomeric proteins of …

To this day, the quest to find new drugs is still a challenge due to the growing demands of
patients suffering from chronic inflammatory diseases and the need for the individualization …