Simple Summary Next-generation sequencing (NGS) is a powerful tool used in genomics
research. NGS can sequence millions of DNA fragments at once, providing detailed …

Metformin is the most commonly used treatment to increase insulin sensitivity in insulin-
resistant (IR) conditions such as diabetes, prediabetes, polycystic ovary syndrome, and …

In the last few years, more and more scientists have suggested and confirmed that
epigenetic regulators are tightly connected and form a comprehensive network of regulatory …

A long-term complication of obesity is the development of type 2 diabetes (T2D). Patients
with T2D have been described as having epigenetic modifications. Epigenetics is the post …

Ketone bodies (KBs) and Sirtuin-1 (SIRT1) have received increasing attention over the past
two decades given their pivotal function in a variety of biological contexts, including …

The current drugs for the treatment of type 2 diabetes mellitus (T2DM) can cause side effects
after long-time use. Hence, the novel drugs were urgent need to developed for T2DM …

Diabetes mellitus (DM) and its related complications are among the leading causes of
disability and mortality worldwide. Substantial studies have explored epigenetic regulation …

Metabolic diseases and their complications impose health and economic burdens
worldwide. Evidence from past experimental studies and clinical trials suggests our body …

Type 2 diabetes mellitus (T2DM) causes peripheral vascular disease because of which
several blood-borne factors, including vital nutrients fail to reach the affected tissue. Tissue …

The burden of growing concern about the dysregulation of metabolic processes arises due
to complex interplay between environment and nutrition that has great impact on genetics …