The fine balance between the secretion, composition, volume and turnover of cerebrospinal
fluid (CSF) is strictly regulated. However, during certain neurological diseases, this balance …

The most common forms of acquired epilepsies arise following acute brain insults such as
traumatic brain injury, stroke, or central nervous system infections. Treatment is effective for …

Traumatic brain injury (TBI) is the leading cause of death in young adults and children. The
treatment of TBI in the acute phase has improved substantially; however, the prevention and …

Objective: To review the underlying pathophysiologic processes of concussive brain injury
and relate these neurometabolic changes to clinical sports-related issues such as injury to …

Animal models of traumatic brain injury (TBI) are used to elucidate primary and secondary
sequelae underlying human head injury in an effort to identify potential neuroprotective …

It has long been recognized that insults to the cerebral cortex, such as trauma, ischaemia or
infections, may result in the development of epilepsy, one of the most common neurological …

This article comprehensively reviews the lateral fluid percussion (LFP) model of traumatic
brain injury (TBI) in small animal species with particular emphasis on its validity, clinical …

Epilepsy refers to a cluster of neurological diseases characterized by seizures. Although
many forms of epilepsy have a well-defined immune etiology, in other forms of epilepsy an …

Perturbations in the integrity of the blood-brain barrier have been reported in both humans
and animals under numerous pathological conditions. Although the blood-brain barrier …

The epilepsies are a diverse spectrum of disease states characterized by spontaneous
seizures and associated comorbidities. Neuron-focused perspectives have yielded an array …