Early life adversity across different cell-types in the brain

G Warhaftig, D Almeida, G Turecki - Neuroscience & Biobehavioral …, 2023 - Elsevier
Early life adversity (ELA)-which includes physical, psychological, emotional, and sexual
abuse is one of the most common predictors to diverse psychopathologies later in …

Reelin alterations, behavioral phenotypes, and brain anomalies in schizophrenia: a systematic review of insights from rodent models

AC Sánchez-Hidalgo, C Martín-Cuevas… - Frontiers in …, 2022 - frontiersin.org
Reelin is an extracellular matrix glycoprotein reduced in brain regions (the prefrontal cortex
and the hippocampus) of patients with schizophrenia. There are diverse rodent models of …

Parvalbumin interneurons and perineuronal nets in the hippocampus and retrosplenial cortex of adult male mice after early social isolation stress and perinatal NMDA …

P Klimczak, A Rizzo, E Castillo-Gómez… - Frontiers in synaptic …, 2021 - frontiersin.org
Both early life aversive experiences and intrinsic alterations in early postnatal
neurodevelopment are considered predisposing factors for psychiatric disorders, such as …

Sex differences in affective dysfunction and alterations in parvalbumin in rodent models of early life adversity

SN Ellis, JA Honeycutt - Frontiers in behavioral neuroscience, 2021 - frontiersin.org
The early life environment markedly influences brain and behavioral development, with
adverse experiences associated with increased risk of anxiety and depressive phenotypes …

Effects of maternal deprivation on the prefrontal cortex of male rats: cellular, neurochemical, and behavioral outcomes

J Poleksic, M Aksic, S Kapor, D Aleksic… - Frontiers in Behavioral …, 2021 - frontiersin.org
Stressful events experienced during early life are associated with increased vulnerability of
developing psychopathology in adulthood. In the present study, we exposed 9-day-old …

The impact of early life maternal deprivation on the perineuronal nets in the prefrontal cortex and hippocampus of young adult rats

A Jakovljevic, G Agatonovic, D Aleksic… - Frontiers in Cell and …, 2022 - frontiersin.org
Early life stress negatively impacts brain development and affects structure and function of
parvalbumin immunopositive (PV+) inhibitory neurons. Main regulators of PV+ interneurons …

[HTML][HTML] The Neuroprotective Effect of Neural Cell Adhesion Molecule L1 in the Hippocampus of Aged Alzheimer's Disease Model Mice

M Aksic, I Jakovcevski, MIK Hamad, V Jakovljevic… - Biomedicines, 2024 - mdpi.com
Alzheimer's disease (AD) is a severe neurodegenerative disorder and the most common
form of dementia, causing the loss of cognitive function. Our previous study has shown …

The long-term effects of maternal deprivation on the number and size of inhibitory interneurons in the rat amygdala and nucleus accumbens

D Aleksic, J Poleksic, G Agatonovic, V Djulejic… - Frontiers in …, 2023 - frontiersin.org
Introduction There is an increasing evidence supporting the hypothesis that traumatic
experiences during early developmental periods might be associated with psychopathology …

Chronic hM3Dq-DREADD-mediated chemogenetic activation of parvalbumin-positive inhibitory interneurons in postnatal life alters anxiety and despair-like behavior …

T Banerjee, S Pati, P Tiwari, VA Vaidya - Journal of Biosciences, 2022 - Springer
Animal models of early adversity or neurodevelopmental disorders are associated with
altered parvalbumin (PV)-positive inhibitory interneuron number and function, correlated …

Morfološke, biohemijske i bihejvioralne promene u medijalnom prefrontalnom i orbitofrontalnom korteksu mozga pacova uslovljene maternalnom deprivacijom

JL Poleksić - 2022 - search.proquest.com
Traumatska iskustva proživljena tokom ranog životnog doba povećavaju mogućnost razvoja
psihičkih oboljenja kasnije tokom života. Kako bi ispitali uticaj ranog traumatskog iskustva …