The choroid plexus (ChP) is the principal source of cerebrospinal fluid (CSF), which has
accepted roles as a fluid cushion and a sink for nervous system waste in vertebrates …

Neurons that synthesize and release 5-hydroxytryptamine (5-HT; serotonin) express a core
set of genes that establish and maintain this neurotransmitter phenotype and distinguish …

Midbrain dopamine (DA) neurons have diverse functions that can in part be explained by
their heterogeneity. Although molecularly distinct subtypes of DA neurons have been …

Dysfunctional dopamine (DA) signaling has been associated with a broad spectrum of
neuropsychiatric disorders, prompting investigations into how midbrain DA neuron …

The choroid plexus (ChP) in each brain ventricle produces cerebrospinal fluid (CSF) and
forms the blood-CSF barrier. Here, we construct a single-cell and spatial atlas of each ChP …

Cellular specialization is particularly prominent in mammalian nervous systems, which are
composed of millions to billions of neurons that appear in thousands of different'flavors' and …

The locus coeruleus (LC) is a seemingly singular and compact neuromodulatory nucleus
that is a prominent component of disparate theories of brain function due to its broad …

Precisely defining the roles of specific cell types is an intriguing frontier in the study of intact
biological systems and has stimulated the rapid development of genetically encoded tools …

The Cre–loxP recombination system is the most widely used technology for in vivo tracing of
stem or progenitor cell lineages. The precision of this genetic system largely depends on the …

In the transgenic multicolor labeling strategy called'Brainbow', Cre-loxP recombination is
used to create a stochastic choice of expression among fluorescent proteins, resulting in the …