Principal component analysis

M Greenacre, PJF Groenen, T Hastie… - Nature Reviews …, 2022 - nature.com
Principal component analysis is a versatile statistical method for reducing a cases-by-
variables data table to its essential features, called principal components. Principal …

Obtaining genetics insights from deep learning via explainable artificial intelligence

G Novakovsky, N Dexter, MW Libbrecht… - Nature Reviews …, 2023 - nature.com
Artificial intelligence (AI) models based on deep learning now represent the state of the art
for making functional predictions in genomics research. However, the underlying basis on …

Counterfactual explanations and how to find them: literature review and benchmarking

R Guidotti - Data Mining and Knowledge Discovery, 2024 - Springer
Interpretable machine learning aims at unveiling the reasons behind predictions returned by
uninterpretable classifiers. One of the most valuable types of explanation consists of …

Measuring biological age using omics data

J Rutledge, H Oh, T Wyss-Coray - Nature Reviews Genetics, 2022 - nature.com
Age is the key risk factor for diseases and disabilities of the elderly. Efforts to tackle age-
related diseases and increase healthspan have suggested targeting the ageing process …

Data-driven capacity estimation of commercial lithium-ion batteries from voltage relaxation

J Zhu, Y Wang, Y Huang, R Bhushan Gopaluni… - Nature …, 2022 - nature.com
Accurate capacity estimation is crucial for the reliable and safe operation of lithium-ion
batteries. In particular, exploiting the relaxation voltage curve features could enable battery …

Influence of the microbiome, diet and genetics on inter-individual variation in the human plasma metabolome

L Chen, DV Zhernakova, A Kurilshikov… - Nature medicine, 2022 - nature.com
The levels of the thousands of metabolites in the human plasma metabolome are strongly
influenced by an individual's genetics and the composition of their diet and gut microbiome …

A guide to machine learning for biologists

JG Greener, SM Kandathil, L Moffat… - Nature reviews Molecular …, 2022 - nature.com
The expanding scale and inherent complexity of biological data have encouraged a growing
use of machine learning in biology to build informative and predictive models of the …

Federated learning for predicting histological response to neoadjuvant chemotherapy in triple-negative breast cancer

J Ogier du Terrail, A Leopold, C Joly, C Béguier… - Nature medicine, 2023 - nature.com
Triple-negative breast cancer (TNBC) is a rare cancer, characterized by high metastatic
potential and poor prognosis, and has limited treatment options. The current standard of …

Stroke genetics informs drug discovery and risk prediction across ancestries

A Mishra, R Malik, T Hachiya, T Jürgenson, S Namba… - Nature, 2022 - nature.com
Previous genome-wide association studies (GWASs) of stroke—the second leading cause of
death worldwide—were conducted predominantly in populations of European ancestry …

Adversarial machine learning for network intrusion detection systems: A comprehensive survey

K He, DD Kim, MR Asghar - IEEE Communications Surveys & …, 2023 - ieeexplore.ieee.org
Network-based Intrusion Detection System (NIDS) forms the frontline defence against
network attacks that compromise the security of the data, systems, and networks. In recent …