Accumulating evidence points to the causal role of triglyceride-rich lipoproteins and their
cholesterol-enriched remnants in atherogenesis. Genetic studies in particular have not only …

Apolipoproteins are important structural components of plasma lipoproteins that influence
vascular biology and atherosclerotic disease pathophysiology by regulating lipoprotein …

Despite the success of LDL-lowering drugs in reducing cardiovascular disease (CVD), there
remains a large burden of residual disease due in part to persistent dyslipidemia …

The positive relationship between increased levels of circulating triglycerides and
cardiovascular events has been observed for decades. Driven by genetic cohort studies …

Cardiovascular disease (CVD) is the leading cause of death globally. It is well-established
based on evidence accrued during the last three decades that high plasma concentrations …

Background Peritoneal metastasis (PM) occurs frequently in patients with gastric cancer
(GC) and confers poor survival. Lipid metabolism acts as a non‐negligible regulator in …

Hypertriglyceridemia (HTG) is a common metabolic disorder with both genetic and lifestyle
factors playing significant roles in its pathophysiology. HTG poses a risk for the development …

Lipoprotein lipase (LPL) plays a major role in the lipid homeostasis mainly by mediating the
intravascular lipolysis of triglyceride rich lipoproteins. Impaired LPL activity leads to the …

Cardiovascular disease (CVD) is still the leading cause of death globally, and
atherosclerosis is the main pathological basis of CVDs. Low-density lipoprotein cholesterol …

Lipolysis of triglyceride-rich lipoproteins by LpL is a central event in lipid metabolism,
releasing fatty acids for uptake by tissues and generating low-density lipoprotein and …