The American Heart Association requests that this document be cited as follows: Grundy SM,
Stone NJ, Bailey AL, Beam C, Birtcher KK, Blumenthal RS, Braun LT, de Ferranti S, Faiella …

Background Non-adherence negatively affects the efficacy, safety and costs of therapies.
Non-adherence is a multifactorial problem. This systematic review (SR) of SRs (overview) …

Despite encouraging advances in prevention and treatment of atherothrombosis,
cardiovascular disease (CVD) remains a major cause of deaths and disability worldwide …

Background Medication non-adherence is one of the major challenges in treating patients
with depression. This systematic review aims to determine the clinical and economic …

Objective Pharmacologic treatment for secondary prevention of coronary heart disease
(CHD) is critical to prevent adverse clinical outcomes. In a randomized controlled trial, we …

Background Prior studies suggest that persistence with and adherence to statin therapy is
low. Interventions to improve statin persistence and adherence have been developed over …

The clinical and economic burden of hypertension is high and continues to increase
globally. Uncontrolled hypertension has severe but avoidable long‐term consequences …

Background Use of cardiovascular medication has increased over time, especially for
primary and secondary prevention, with polypharmacy common. Methods Review of …

Improving medication adherence across the health care system is an ingredient that is vital
to improving patient outcomes and reducing downstream health care costs. The …

This review explores the impact of gender on medication adherence in the context of
metabolic and cardiovascular diseases. Optimal adherence to medication is crucial for …