Toll‐like receptors (TLRs): structure, functions, signaling, and role of their polymorphisms in colorectal cancer susceptibility

AS Sameer, S Nissar - BioMed Research International, 2021 - Wiley Online Library
Toll‐like receptors (TLRs) are the important mediators of inflammatory pathways in the gut
which play a major role in mediating the immune responses towards a wide variety of …

Dietary lipids, gut microbiota and lipid metabolism

M Schoeler, R Caesar - Reviews in endocrine and metabolic disorders, 2019 - Springer
The gut microbiota is a central regulator of host metabolism. The composition and function of
the gut microbiota is dynamic and affected by diet properties such as the amount and …

Toll-like receptors in immunity and inflammatory diseases: Past, present, and future

K Vijay - International immunopharmacology, 2018 - Elsevier
The immune system is a very diverse system of the host that evolved during evolution to
cope with various pathogens present in the vicinity of environmental surroundings inhabited …

Chitosan oligosaccharide (COS): An overview

M Naveed, L Phil, M Sohail, M Hasnat… - International journal of …, 2019 - Elsevier
The frequently studied polysaccharide, chitosan oligosaccharide/chitooligosaccharide
(COS) is the major degradation product of chitosan/chitin via chemical hydrolysis or …

Anti-inflammatory action of statins in cardiovascular disease: the role of inflammasome and toll-like receptor pathways

K Koushki, SK Shahbaz, K Mashayekhi… - Clinical reviews in …, 2021 - Springer
Atherosclerosis is one type of cardiovascular disease (CVD) in which activation of the
NLRP3 inflammasome and toll-like receptor (TLR) pathways is implicated. One of the most …

[HTML][HTML] Resistance mechanisms to immune-checkpoint blockade in cancer: tumor-intrinsic and-extrinsic factors

JM Pitt, M Vétizou, R Daillère, MP Roberti, T Yamazaki… - Immunity, 2016 - cell.com
Inhibition of immune regulatory checkpoints, such as CTLA-4 and the PD-1-PD-L1 axis, is at
the forefront of immunotherapy for cancers of various histological types. However, such …

Preparation and biological activities of chitosan oligosaccharides

G Benchamas, G Huang, S Huang, H Huang - Trends in Food Science & …, 2021 - Elsevier
Abstract Background Chitosan oligosaccharides (COSs) are the degraded products
prepared from the deacetylation and depolymerization of chitin or chitosan using physical …

Role of gut microbiota in atherosclerosis

AL Jonsson, F Bäckhed - Nature Reviews Cardiology, 2017 - nature.com
Infections have been linked to the development of cardiovascular disease and
atherosclerosis. Findings from the past decade have identified microbial ecosystems …

Acute respiratory distress syndrome

MA Matthay, RL Zemans, GA Zimmerman… - Nature reviews Disease …, 2019 - nature.com
The acute respiratory distress syndrome (ARDS) is a common cause of respiratory failure in
critically ill patients and is defined by the acute onset of noncardiogenic pulmonary oedema …

Immunological mechanisms of human resistance to persistent Mycobacterium tuberculosis infection

JD Simmons, CM Stein, C Seshadri, M Campo… - Nature Reviews …, 2018 - nature.com
Mycobacterium tuberculosis is a leading cause of mortality worldwide and establishes a
long-lived latent infection in a substantial proportion of the human population. Multiple lines …