A review on antioxidants, prooxidants and related controversy: Natural and synthetic compounds, screening and analysis methodologies and future perspectives

M Carocho, ICFR Ferreira - Food and chemical toxicology, 2013 - Elsevier
Many studies have been conducted with regard to free radicals, oxidative stress and
antioxidant activity of food, giving antioxidants a prominent beneficial role, but, recently …

Antioxidants and human diseases

P Rajendran, N Nandakumar, T Rengarajan… - Clinica chimica acta, 2014 - Elsevier
Oxidative stress plays a pivotal role in the development of human diseases. Reactive
oxygen species (ROS) that includes hydrogen peroxide, hyphochlorus acid, superoxide …

Curcumin attenuates oxidative stress in RAW264. 7 cells by increasing the activity of antioxidant enzymes and activating the Nrf2-Keap1 pathway

X Lin, D Bai, Z Wei, Y Zhang, Y Huang, H Deng… - PloS one, 2019 - journals.plos.org
Large-scale breeding environments often lead to oxidative stress. Macrophages play an
important role in the immune system and are vulnerable to reactive oxygen species (ROS) …

[HTML][HTML] Honey: a novel antioxidant

OO Erejuwa, SA Sulaiman, MS Ab Wahab - Molecules, 2012 - mdpi.com
The global prevalence of chronic diseases such as diabetes mellitus, hypertension,
atherosclerosis, cancer and Alzheimer's disease is on the rise. These diseases, which …

Potential health benefits of anthocyanins in oxidative stress related disorders

MA Alam, P Islam, N Subhan, MM Rahman… - Phytochemistry …, 2021 - Springer
Anthocyanins are naturally occurring water-soluble plant pigments belonging to the
flavonoids chemical class. The red, blue and purple colours of leaves, flowers and fruits of …

Free radicals: health implications and their mitigation by herbals

S Kumar, A Pandey - British Journal of Medicine and Medical …, 2015 - journal.send2sub.com
Free radicals pose a serious threat to tissues and vital organs, especially membrane lipids,
proteins and nucleic acids of cells. Overproduction of reactive oxygen/nitrogen species …

New organochalcogen multitarget drug: Synthesis and antioxidant and antitumoral activities of chalcogenozidovudine derivatives

D de Souza, DOC Mariano, F Nedel… - Journal of medicinal …, 2015 - ACS Publications
In this article we present the synthesis, characterization, and in vitro biological and
biochemical activities of new chalcogenozidovudine derivatives as antioxidant (inhibition of …

Design, synthesis, molecular modelling and biological evaluation of novel 3-(2-naphthyl)-1-phenyl-1H-pyrazole derivatives as potent antioxidants and 15 …

SA Ali, SM Awad, AM Said, S Mahgoub… - Journal of enzyme …, 2020 - Taylor & Francis
Oxidative stress is one of the main causes of significant severe diseases. The discovery of
new potent antioxidants with high efficiency and low toxicity is a great demand in the field of …

Concentration dependence of the antioxidant and prooxidant activity of trolox in hela cells: Involvement in the induction of apoptotic volume decrease

ME Giordano, R Caricato, MG Lionetto - Antioxidants, 2020 - mdpi.com
Trolox (6-hydroxy-2, 5, 7, 8-tetramethylchroman-2-carboxylic acid), a hydrophilic analog of
vitamin E, is known for its strong antioxidant activity, being a high radical scavenger of …

Rape bee pollen alleviates dextran sulfate sodium (DSS)-induced colitis by neutralizing IL-1β and regulating the gut microbiota in mice

S Chen, H Zhao, N Cheng, W Cao - Food research international, 2019 - Elsevier
Colitis is a major chronic disease in today's society. Consumption of phenolic compounds
can protect against colitis. We examined the phenolic compounds of rape bee pollen extract …