The aging process is driven at the cellular level by random molecular damage that slowly
accumulates with age. Although cells possess mechanisms to repair or remove damage …

Diabetic peripheral neuropathy (DPN) is one of the most widespread and disabling
neurological conditions, accounting for half of all neuropathy cases worldwide. Despite its …

It is highly desired to explore the interventions of COVID-19 for early treatment strategies.
Such interventions are still under consideration. A model is benchmarked research and …

The chronic Philadelphia-negative myeloproliferative neoplasms (MPNs) are acquired stem
cell neoplasms which ultimately may transform to acute myelogenous leukemia. Most …

Macrophages are central to the inflammatory response and its ability to resolve effectively.
They are complex cells that adopt a range of subtypes depending on the tissue type and …

Rheumatoid arthritis (RA) is a complex autoimmune disease with an unknown aetiology.
However, rheumatoid arthritis fibroblast-like synoviocytes (RA-FLS) play a significant role in …

In the work presented here, a novel mathematical model was developed to explore the bi-
directional communication between the hypothalamic-pituitary-adrenal (HPA) axis and …

Simple Summary Fibroblasts are critical regulators of several physiological processes linked
to extracellular matrix regulation. Under certain conditions, fibroblasts can also transform …

Problem The immunoregulation to tolerate the semiallogeneic fetus during pregnancy
includes a harmonious dynamic balance between anti‐and pro‐inflammatory cytokines …

Inflammatory responses to an infection from a zoonotic pathogen, such as avian influenza
viruses, hantaviruses and some coronaviruses, are distinctly different in their natural …