Conspectus Catalytic atroposelective syntheses of axially chiral compounds have stimulated
extensive interest in multiple communities, such as synthetic chemistry, biochemistry, and …

Atropisomerism is a stereochemical behavior portrayed by three-dimensional molecules that
bear rotationally restricted σ bond. Akin to the well-represented point-chiral molecules …

This study establishes the first organocatalytic enantioselective synthesis of axially chiral N,
N′‐bisindoles via chiral phosphoric acid‐catalyzed formal (3+ 2) cycloadditions of indole …

Enantiomers, where chirality arises from restricted rotation around a single bond, are
atropisomers. Due to the unique nature of the origins of their chirality, synthetic strategies to …

The first highly atroposelective construction of N− N axially chiral indole scaffolds was
established via a new strategy of de novo ring formation. This strategy makes use of the …

Molecules with restricted rotation around a single bond or atropisomers are found in a wide
number of natural products and bioactive molecules as well as in chiral ligands for …

Transition metal‐catalyzed enantioselective functionalization of C− H bond, the most
abundant functionality in organic molecules, has emerged as an expedient synthetic …

Direct catalytic transformation of C–H bonds to new functionalities has provided a powerful
strategy to synthesize complex molecular scaffolds in a straightforward way. Unstinting …

Conspectus Axially chiral compounds have received much attention from chemists because
of their widespread appearance in natural products, biologically active compounds, and …

Axially chiral biaryl motifs are widely present in natural products and pharmaceuticals.
Moreover, they have been broadly used as privileged ligands in asymmetric catalysis. Over …