It is well known that most brain disorders are complex diseases, such as Alzheimer's
disease (AD) and schizophrenia (SCZ). In general, brain regions and their interactions can …

Background Neuroimaging studies help us better understand the pathophysiology and
symptoms of Parkinson's disease (PD). In several of these studies, diffusion tensor imaging …

Parkinson's disease (PD) is a neurodegenerative disorder with dysfunction in cortices as
well as white matter (WM) tracts. While the changes to WM structure have been extensively …

Diffusion tensor imaging (DTI) allows measuring fractional anisotropy and similar
microstructural indices of the brain white matter. Lower than normal fractional anisotropy as …

Abstract Purpose of Review Mild cognitive impairment is a common feature of Parkinson's
disease, even at the earliest disease stages, but there is variation in the nature and severity …

Background Whether structural alterations underpin apathy and depression in de novo
parkinsonian patients is unknown. The objectives of this study were to investigate whether …

Background Disturbance of gait is a key feature of Parkinson's disease (PD) and has a
negative impact on quality of life. Deficits in cognition and sensorimotor processing impair …

Parkinson's disease (PD) often shows disrupted brain connectivity and autonomic
dysfunctions, progressing alongside with motor and cognitive decline. Recently, PD has …

Parkinson's disease (PD) is a progressive neurodegenerative disorder that affects extensive
regions of the central nervous system. In this work, we evaluated the structural connectome …

Recent graph-theoretical studies of Parkinson's disease (PD) have examined alterations in
the global properties of the brain structural connectome; however, reported alterations are …