The Annonaceous acetogenins are promising new antitumor and pesticidal agents that are
found only in the plant family Annonaceae. Chemically, they are derivatives of long-chain …

The aldol reaction is a cornerstone of synthetic organic chemistry and has been the subject
of considerable optimization, especially in terms of diastereo-and enantiocontrol. 1 The …

Reactions between N-acyliminium ions and nucleophiles–also described as
amidoalkylation or Mannich type condensations–have been frequently utilized to introduce …

Contents 1. Introduction 3221 2. Acyclic iminium ions reacting with acyclic dienols 3222 2.1.
N-Acyl and trialkyl iminium ions 3222 2.2. O-Silylated nitrones 3222 2.3. Imine±Lewis acid …

The aim of this review is to highlight the utility of a remarkable triad of 2-silyloxy diene
synthons derived from furan, pyrrole and thiophene in organic synthesis. These …

A procedure that enables high yielding access to phosphonic γ‐(hydroxyalkyl) butenolides
with excellent regio‐, diastereo‐and enantiocontrol is reported. The simultaneous …

All eight diastereoisomers of the monotetrahydrofuran‐ring cores of annonaceous
acetogenins have been synthesized through utilization of asymmetric alkynylation and …

Natural linear polyamines play diverse roles in physiological processes by interacting with
receptors at the cellular level. Herein, we describe the stereodivergent synthesis of …

Alkyl substituted lactol acetates have been found to undergo highly stereoselective
substitution reactions mediated by tin (IV) bromide. The highest selectivity is observed in the …

Four stereoisomers of the THF cores, synthetic intermediates of acetogenins, have been
synthesized with high diastereoselectivity by asymmetric alkynylation and subsequent …