An amino acid-resolution interactome for motile cilia identifies the structure and function of ciliopathy protein complexes

CL McCafferty, O Papoulas, C Lee, KH Bui… - Developmental Cell, 2024 - cell.com
Motile cilia are ancient, evolutionarily conserved organelles whose dysfunction underlies
motile ciliopathies, a broad class of human diseases. Motile cilia contain a myriad of different …

Label-free proteomic comparison reveals ciliary and nonciliary phenotypes of IFT-A mutants

JC Leggere, JVK Hibbard, O Papoulas… - Molecular Biology of …, 2024 - Am Soc Cell Biol
DIFFRAC is a powerful method for systematically comparing proteome content and
organization between samples in a high-throughput manner. By subjecting control and …