Post-translational modification with O-linked β-N-acetylglucosamine (O-GlcNAc), a process
referred to as O-GlcNAcylation, occurs on a vast variety of proteins. Mounting evidence in …

The modification of nuclear, mitochondrial, and cytosolic proteins by O-linked βN-
acetylglucosamine (O-GlcNAc) has emerged as a dynamic and essential post-translational …

O-GlcNAcylation is a conserved post-translational modification that attaches N-acetyl
glucosamine (GlcNAc) to myriad cellular proteins. In response to nutritional and hormonal …

The modification of intracellular proteins with O-linked β-N-acetylglucosamine (O-GlcNAc)
moieties is a highly dynamic process that spatiotemporally regulates nearly every important …

The O-linked β-N-acetylglucosamine modification is a core signalling mechanism, with
erroneous patterns leading to cancer and neurodegeneration. Although thousands of …

The modification of nucleocytoplasmic proteins by O-linked N-acetylglucosamine (O-
GlcNAc) is an important regulator of cell physiology. O-GlcNAc is installed on over a …

O-GlcNAc transferase (OGT) is an essential mammalian enzyme that binds thousands of
different proteins, including substrates that it glycosylates and nonsubstrate interactors that …

Abstract Eukaryotic RNA polymerase II (RNAPII) is responsible for the transcription of the
protein-coding genes in the cell. Enormous progress has been made in discovering the …

O-Linked β-N-acetylglucosamine (O-GlcNAc) is an essential, dynamic monosaccharide post-
translational modification (PTM) found on serine and threonine residues of thousands of …

Protein O-linked β-N-acetylglucosamine modification (O-GlcNAcylation) plays a crucial role
in regulating essential cellular processes. The disruption of the homeostasis of O …