Mycobacterium tuberculosis (Mtb) is the causative agent of human tuberculosis (TB) which
primarily infects the macrophages. Nearly a quarter of the world's population is infected …

The Mycobacterium tuberculosis complex (MTBC) consists of closely related species that
cause tuberculosis in both humans and animals. This illness, still today, remains to be one of …

Iron is one of the major limiting factors and essential nutrients of microbial life. Since in
nature it is not readily available in the preferred form, microorganisms produce small high …

Application of microbes or their products in our life is increasing as research on microbiology
is proceeding. Many scientists are now paying much interest on research and proper …

The Esx secretion pathway is conserved across Gram-positive bacteria. Esx-1, the best-
characterized system, is required for virulence of Mycobacterium tuberculosis, although its …

The highly contagious disease tuberculosis (TB) is caused by the bacterium Mycobacterium
tuberculosis (Mtb), which has been evolving drug resistance at an alarming rate. Like all …

Mycobacterium tuberculosis is a prototrophic, metabolically flexible bacterium that has
achieved a spread in the human population that is unmatched by any other bacterial …

M. tuberculosis (Mtb) survives a hostile environment within the host that is shaped in part by
oxidative stress. The mechanisms used by Mtb to resist these stresses remain ill-defined …

Since their discovery in the 1960s as 'osmotic shock-sensitive'transporters, a plethora of so-
called binding protein-dependent (canonical) ATP-binding cassette (ABC) importers has …

The capacity of Mycobacterium tuberculosis (Mtb) to tolerate multiple antibiotics represents a
major problem in tuberculosis (TB) management. Heterogeneity in Mtb populations is one of …