Metastasis review: from bench to bedside

AM Alizadeh, S Shiri, S Farsinejad - Tumor biology, 2014 - Springer
Cancer is the final result of uninhibited cell growth that involves an enormous group of
associated diseases. One major aspect of cancer is when cells attack adjacent components …

Tumor-reactive antibodies evolve from non-binding and autoreactive precursors

RD Mazor, N Nathan, A Gilboa, L Stoler-Barak, L Moss… - Cell, 2022 - cell.com
The tumor microenvironment hosts antibody-secreting cells (ASCs) associated with a
favorable prognosis in several types of cancer. Patient-derived antibodies have diagnostic …

[HTML][HTML] circ-CSPP1 promotes proliferation, invasion and migration of ovarian cancer cells by acting as a miR-1236-3p sponge

Q Li, Y Liu, S Chen, Z Zong, Y Du, X Sheng… - Biomedicine & …, 2019 - Elsevier
Circular RNAs are known to participate in tumorigenesis through a variety of pathways, and
as such, have potential to serve as molecular markers in tumor diagnosis and treatment …

Estrogen induced metastatic modulators MMP-2 and MMP-9 are targets of 3, 3′-diindolylmethane in thyroid cancer

S Rajoria, R Suriano, A George, A Shanmugam… - PloS one, 2011 - journals.plos.org
Background Thyroid cancer is the most common endocrine related cancer with increasing
incidences during the past five years. Current treatments for thyroid cancer, such as surgery …

MMPs in ovarian cancer as therapeutic targets

A Karam, O Dorigo - Anti-Cancer Agents in Medicinal …, 2012 - ingentaconnect.com
In the United States, about 22,000 women will be diagnosed with ovarian cancer in 2011,
and an estimated 14,000 patients will succumb to the disease [1]. Surgery and …

Activation of the PKC pathway stimulates ovarian cancer cell proliferation, migration, and expression of MMP7 and MMP10

LF Al-Alem, LA McCord, RC Southard… - Biology of …, 2013 - academic.oup.com
Postmenopausal women are at a higher risk of ovarian cancer due, in part, to increased
levels of gonadotropins such as luteinizing hormone (LH). Gonadotropins and other stimuli …

Anti-metastatic and anti-angiogenic properties of potential new anti-cancer drugs based on metal complexes of selenosemicarbazones

M Zec, T Srdic-Rajic, A Konic-Ristic… - Anti-Cancer Agents …, 2012 - ingentaconnect.com
Our previous studies showed that zinc (II), cadmium (II) and nickel (II) complexes with 2-
formylpyridine selenosemicarbazone induce apoptosis in cancer cells via activation of …

The relevance and role of vascular endothelial growth factor C, matrix metalloproteinase-2 and E-cadherin in epithelial ovarian cancer

KJ Huang, LH Sui - Medical oncology, 2012 - Springer
We investigated the correlation of vascular endothelial growth factor C, matrix
metalloproteinase-2, E-cadherin to explore mechanisms of vascular endothelial growth …

Pathological and prognostic significance of matrix metalloproteinase-2 expression in ovarian cancer: a meta-analysis

C Liu - Clinical and experimental medicine, 2016 - Springer
Abstract Matrix metalloproteinase-2 (MMP-2) has been linked with tumor invasion and
metastasis. However, the role of MMP-2 expression in ovarian cancer remains controversial …

Worse prognosis in breast cancer patients can be predicted by immunohistochemical analysis of positive MMP-2 and negative estrogen and progesterone receptors

EAS Ramos, CT Silva, GCM Manica… - Revista da Associação …, 2016 - SciELO Brasil
Introduction: Breast cancer is the most cause of death, and approximately 90% of these
deaths are due to metastases. Matrix metalloproteinase-2 (MMP-2) gelatinase activity is able …