Structure-activity association of flavonoids in lung diseases

JHG Lago, AC Toledo-Arruda, M Mernak, KH Barrosa… - Molecules, 2014 - mdpi.com
Flavonoids are polyphenolic compounds classified into flavonols, flavones, flavanones,
isoflavones, catechins, anthocyanidins, and chalcones according to their chemical …

Eosinophilic inflammation in allergic asthma

SS Possa, EA Leick, CM Prado, MA Martins… - Frontiers in …, 2013 - frontiersin.org
Eosinophils are circulating granulocytes involved in pathogenesis of asthma. A cascade of
processes directed by Th2 cytokine producing T-cells influence the recruitment of …

[HTML][HTML] Chronic effects of air pollution on respiratory health in Southern California children: findings from the Southern California Children's Health Study

Z Chen, MT Salam, SP Eckel, CV Breton… - Journal of thoracic …, 2015 - ncbi.nlm.nih.gov
Outdoor air pollution is one of the leading contributors to adverse respiratory health
outcomes in urban areas around the world. Children are highly sensitive to the adverse …

Endogenous hydrogen sulfide reduces airway inflammation and remodeling in a rat model of asthma

YH Chen, R Wu, B Geng, YF Qi, PP Wang, WZ Yao… - Cytokine, 2009 - Elsevier
Endogenous hydrogen sulfide (H2S) is hypothesized to have an important role in systemic
inflammation. We investigated if endogenous H2S may be a crucial mediator in airway …

Nitric oxide in asthma physiopathology

CM Prado, MA Martins… - International Scholarly …, 2011 - Wiley Online Library
Asthma is a chronic inflammatory airway disease characterized by allergen‐induced airway
hyperresponsiveness, airway inflammation, and remodeling. Nitric oxide (NO) derived from …

Eosinophils in inflammatory bowel disease

RT Filippone, L Sahakian… - Inflammatory bowel …, 2019 - academic.oup.com
Clinical investigations in inflammatory bowel disease (IBD) patients have provided
increasing evidence that eosinophils contribute to chronic intestinal inflammation …

Selective inducible nitric oxide synthase inhibition has no effect on allergen challenge in asthma

D Singh, D Richards, RG Knowles… - American journal of …, 2007 - atsjournals.org
Rationale: Exhaled breath nitric oxide (FeNO) is increased in asthma. NO is produced
predominantly by inducible nitric oxide synthase (iNOS). Objectives: We evaluated the …

Evidences of herbal medicine‐derived natural products effects in inflammatory lung diseases

FPR Santana, NM Pinheiro, MIB Mernak… - Mediators of …, 2016 - Wiley Online Library
Pulmonary inflammation is a hallmark of many respiratory diseases such as asthma, chronic
obstructive pulmonary disease (COPD), and acute respiratory syndrome distress (ARDS) …

Flavonone treatment reverses airway inflammation and remodelling in an asthma murine model

AC Toledo, CPP Sakoda, A Perini… - British Journal of …, 2013 - Wiley Online Library
Background and Purpose Asthma is an inflammatory disease that involves airway
hyperresponsiveness and remodelling. Flavonoids have been associated to anti …

Nitric oxide metabolism in asthma pathophysiology

S Ghosh, SC Erzurum - Biochimica et Biophysica Acta (BBA)-General …, 2011 - Elsevier
BACKGROUND: Asthma, a chronic inflammatory disease is typically characterized by
bronchoconstriction and airway hyper-reactivity. SCOPE OF REVIEW: A wealth of studies …