Interleukins and associated cytokines serve as the means of communication for innate and
adaptive immune cells as well as non-immune cells and tissues. Thus, interleukins have a …

Immunotherapy has achieved limited success in patients with triple-negative breast cancer
(TNBC), an aggressive disease with a poor prognosis. Commensal microbiota have been …

Natural soluble antagonist and decoy receptor on the surface of the cell membrane are
evolving as crucial immune system regulators as these molecules are capable of …

Melanoma response to immune-modulating therapy remains incompletely characterized at
the molecular level. In this study, we assess melanoma immunotherapy response using a …

Cytokines are the first modern immunotherapeutic agents used for activation
immunotherapy. Interleukin-18 (IL-18) has emerged as a potent anticancer …

The chronic inflammation present in aged individuals is generally depicted as a detrimental
player for longevity. Here, it is discussed several beneficial effects associated with the …

Antibody or antibody-like protein drugs related to tumor immunotherapy are now widely
used. Here, we describe an antibody-fusion protein drug IMAB362-mIL-21 with mouse IL-21 …

Abstract Interleukin‐18 (IL‐18) is a vital pro‐inflammatory cytokine crucial for immune
regulation. Despite its significance, bibliometric analysis in this field is lacking. This study …

Abstract Background Interleukin-18 (IL-18), or interferon (IFN)-γ-inducing factor, potentiates
T helper 1 and natural killer cell activation as well as CD8+ T-cell proliferation. Recombinant …

IL-37 is a newly discovered member of the IL-1 cytokine family which plays an important role
in regulating inflammation and maintaining physiological homeostasis. IL-37 showed a …