Pancreatitis is inflammation of pancreas and caused by a number of factors including
pancreatic duct obstruction, alcoholism, and mutation in the cationic trypsinogen gene …

Eosinophilic esophagitis (EoE) is a chronic immune-mediated disease of the esophagus
characterized clinically by symptoms related to esophageal dysfunction and histologically by …

Eosinophilic esophagitis (EoE) is a chronic inflammatory disease characterized by
eosinophilic infiltration of the esophagus. It arises from a complex interplay of genetic …

Eosinophils are circulating granulocytes that have pleiotropic effects in response to
inflammatory signals in the body. In response to allergens or pathogens, exposure …

The current report describes a stepwise mechanistic pathway of NLRP3/caspase1/IL-18-
regulated immune responses operational in eosinophilic esophagitis (EoE). We show that …

Background Proton pump inhibitors (PPIs) have been recognized as a primary treatment of
eosinophilic esophagitis (EoE), an allergic inflammatory disease of the esophageal mucosa …

Originally described as an interferon (IFN)-γ-inducing factor, interleukin (IL)-18 has been
reported to be involved in Th1 and Th2 immune responses, as well as in activation of NK …

Eosinophilic esophagitis (EoE) is a chronic allergic inflammatory disease that is triggered by
food and/or environmental allergens and is characterized by a clinical and pathologic …

Allergic rhinitis (AR) is a chronic allergic disease of the upper respiratory system that affects
approximately 10–40% of the global population. Due to the large number of plant pollen …

Abstract Interleukin (IL)-18 is an IL-1 family cytokine expressed by macrophages, dendritic
cells, epithelial cells, and keratinocytes and is implicated in various aspects of both the …