Historical perspective of traditional indigenous medical practices: the current renaissance and conservation of herbal resources

SY Pan, G Litscher, SH Gao, SF Zhou… - Evidence‐Based …, 2014 - Wiley Online Library
In recent years, increasing numbers of people have been choosing herbal medicines or
products to improve their health conditions, either alone or in combination with others. Herbs …

Network pharmacology applications to map the unexplored target space and therapeutic potential of natural products

M Kibble, N Saarinen, J Tang, K Wennerberg… - Natural product …, 2015 - pubs.rsc.org
Covering: 2011 to 2014 It is widely accepted that drug discovery often requires a systems-
level polypharmacology approach to tackle problems such as lack of efficacy and emerging …

HERB: a high-throughput experiment-and reference-guided database of traditional Chinese medicine

SS Fang, L Dong, L Liu, JC Guo, LH Zhao… - Nucleic acids …, 2021 - academic.oup.com
Pharmacotranscriptomics has become a powerful approach for evaluating the therapeutic
efficacy of drugs and discovering new drug targets. Recently, studies of traditional Chinese …

ETCM: an encyclopaedia of traditional Chinese medicine

HY Xu, YQ Zhang, ZM Liu, T Chen, CY Lv… - Nucleic acids …, 2019 - academic.oup.com
Traditional Chinese medicine (TCM) is not only an effective solution for primary health care,
but also a great resource for drug innovation and discovery. To meet the increasing needs …

SymMap: an integrative database of traditional Chinese medicine enhanced by symptom mapping

Y Wu, F Zhang, K Yang, S Fang, D Bu, H Li… - Nucleic acids …, 2019 - academic.oup.com
Recently, the pharmaceutical industry has heavily emphasized phenotypic drug discovery
(PDD), which relies primarily on knowledge about phenotype changes associated with …

BATMAN-TCM: a bioinformatics analysis tool for molecular mechANism of traditional Chinese medicine

Z Liu, F Guo, Y Wang, C Li, X Zhang, H Li, L Diao… - Scientific reports, 2016 - nature.com
Abstract Traditional Chinese Medicine (TCM), with a history of thousands of years of clinical
practice, is gaining more and more attention and application worldwide. And TCM-based …

HIT 2.0: an enhanced platform for Herbal Ingredients' Targets

D Yan, G Zheng, C Wang, Z Chen, T Mao… - Nucleic acids …, 2022 - academic.oup.com
Literature-described targets of herbal ingredients have been explored to facilitate the
mechanistic study of herbs, as well as the new drug discovery. Though several databases …

TCMSP: a database of systems pharmacology for drug discovery from herbal medicines

J Ru, P Li, J Wang, W Zhou, B Li, C Huang, P Li… - Journal of …, 2014 - Springer
Background Modern medicine often clashes with traditional medicine such as Chinese
herbal medicine because of the little understanding of the underlying mechanisms of action …

New perspectives on how to discover drugs from herbal medicines: CAM′ S outstanding contribution to modern therapeutics

SY Pan, SF Zhou, SH Gao, ZL Yu… - Evidence‐Based …, 2013 - Wiley Online Library
With tens of thousands of plant species on earth, we are endowed with an enormous wealth
of medicinal remedies from Mother Nature. Natural products and their derivatives represent …

TCMID: traditional Chinese medicine integrative database for herb molecular mechanism analysis

R Xue, Z Fang, M Zhang, Z Yi, C Wen… - Nucleic acids …, 2012 - academic.oup.com
As an alternative to modern western medicine, Traditional Chinese Medicine (TCM) is
receiving increasingly attention worldwide. Great efforts have been paid to TCM's …