Structure and aggregation mechanisms in amyloids

ZL Almeida, RMM Brito - Molecules, 2020 - mdpi.com
The aggregation of a polypeptide chain into amyloid fibrils and their accumulation and
deposition into insoluble plaques and intracellular inclusions is the hallmark of several …

Protein aggregation—Pathways and influencing factors

W Wang, S Nema, D Teagarden - International journal of pharmaceutics, 2010 - Elsevier
Proteins generally will tend to aggregate under a variety of environmental conditions in
comparison with small drug molecules. The extent of aggregation is dependent on many …

Photo-oxidation of proteins

DI Pattison, AS Rahmanto, MJ Davies - … & Photobiological Sciences, 2012 - pubs.rsc.org
Photo-induced damage to proteins occurs via multiple pathways. Direct damage induced by
UVB (λ 280–320 nm) and UVA radiation (λ 320–400 nm) is limited to a small number of …

Dynamic light scattering (DLS) principles, perspectives, applications to biological samples

S Falke, C Betzel - Radiation in bioanalysis: Spectroscopic techniques …, 2019 - Springer
Focus a laser on dissolved particles and analyze the scattered light to reveal their size. This
well established principle is used in dynamic light scattering (DLS), or also called photon …

A brief overview of amyloids and Alzheimer's disease

SY Ow, DE Dunstan - Protein Science, 2014 - Wiley Online Library
Amyloid fibrils are self‐assembled fibrous protein aggregates that are associated with a
number of presently incurable diseases such as Alzheimer's and Parkinson's disease …

Ultraviolet/persulfate (UV/PS) pretreatment of typical natural organic matter (NOM): variation of characteristics and control of membrane fouling

Z Wang, Y Wan, P Xie, A Zhou, J Ding, J Wang… - Chemosphere, 2019 - Elsevier
The effects of ultraviolet/persulfate (UV/PS) pretreatment on ultrafiltration (UF) membrane
fouling caused by typical natural organic matter (NOM) fractions including humic acid (HA) …

Energy landscapes for proteins: From single funnels to multifunctional systems

K Röder, JA Joseph, BE Husic… - Advanced Theory and …, 2019 - Wiley Online Library
This report advances the hypothesis that multifunctional systems may be associated with
multifunnel potential and free energy landscapes, with particular focus on biomolecules. It …

Assessing Health Span in Caenorhabditis elegans: Lessons From Short-Lived Mutants

JA Rollins, AC Howard, SK Dobbins… - … Series A: Biomedical …, 2017 - academic.oup.com
Genetic changes resulting in increased life span are often positively associated with
enhanced stress resistance and somatic maintenance. A recent study found that certain long …

Carnosic acid and carnosol display antioxidant and anti-prion properties in in vitro and cell-free models of prion diseases

K Karagianni, S Pettas, E Kanata, E Lioulia, K Thune… - Antioxidants, 2022 - mdpi.com
Prion diseases are transmissible encephalopathies associated with the conversion of the
physiological form of the prion protein (PrPC) to the disease-associated (PrPSc). Despite …

Determination of the critical pH for unfolding water-soluble cod protein and its effect on encapsulation capacities

Y Wang, J Shen, B Zou, L Zhang, X Xu, C Wu - Food Research International, 2023 - Elsevier
Hydrophobic polyphenols, with a variety of physiological activities, are often practically
limited due to their low water solubility and chemical instability, among which curcumin (Cur) …