Autoantibodies to synaptic receptors and neuronal cell surface proteins in autoimmune diseases of the central nervous system

J Dalmau, C Geis, F Graus - Physiological reviews, 2017 - journals.physiology.org
Investigations in the last 10 years have revealed a new category of neurological diseases
mediated by antibodies against cell surface and synaptic proteins. There are currently 16 …

Paraneoplastic syndromes: an approach to diagnosis and treatment

LC Pelosof, DE Gerber - Mayo Clinic Proceedings, 2010 - Elsevier
Recent medical advances have improved the understanding, diagnosis, and treatment of
paraneoplastic syndromes. These disorders arise from tumor secretion of hormones …

Recommended diagnostic criteria for paraneoplastic neurological syndromes

F Graus, JY Delattre, JCE Antoine, J Dalmau… - Journal of Neurology …, 2004 - jnnp.bmj.com
Background: Paraneoplastic neurological syndromes (PNS) are defined by the presence of
cancer and exclusion of other known causes of the neurological symptoms, but this criterion …

Screening for tumours in paraneoplastic syndromes: report of an EFNS task force

MJ Titulaer, R Soffietti, J Dalmau… - European journal of …, 2011 - Wiley Online Library
Background: Paraneoplastic neurological syndromes (PNS) almost invariably predate
detection of the malignancy. Screening for tumours is important in PNS as the tumour …

Paraneoplastic syndromes of the CNS

J Dalmau, MR Rosenfeld - The Lancet Neurology, 2008 - thelancet.com
Major advances in the management of paraneoplastic neurologic disorders (PND) include
the detection of new antineuronal antibodies, the improved characterisation of known …

Lambert–Eaton myasthenic syndrome: from clinical characteristics to therapeutic strategies

MJ Titulaer, B Lang, JJGM Verschuuren - The Lancet Neurology, 2011 - thelancet.com
Lambert–Eaton myasthenic syndrome (LEMS) is a neuromuscular autoimmune disease that
has served as a model for autoimmunity and tumour immunology. In LEMS, the …

Paraneoplastic neurological syndromes: a practical approach to diagnosis and management

S Binks, C Uy, J Honnorat, SR Irani - Practical Neurology, 2022 - pn.bmj.com
Paraneoplastic neurological syndromes (PNS) are the immune-mediated effects of a remote
cancer and are characterised by an autoantibody response against antigens expressed by …

Central nervous system neuronal surface antibody associated syndromes: review and guidelines for recognition

L Zuliani, F Graus, B Giometto, C Bien… - Journal of Neurology …, 2012 - jnnp.bmj.com
The concept of antibody mediated CNS disorders is relatively recent. The classical CNS
paraneoplastic neurological syndromes are thought to be T cell mediated, and the …

Antibodies and neuronal autoimmune disorders of the CNS

F Graus, A Saiz, J Dalmau - Journal of neurology, 2010 - Springer
We review the neuronal antibodies described in CNS disorders in order to clarify their
diagnostic value, emphasize potentials pitfalls and limitations in the diagnosis of …

Paraneoplastic neurological syndromes

J Honnorat, JC Antoine - Orphanet journal of rare diseases, 2007 - Springer
Paraneoplastic neurological syndromes (PNS) can be defined as remote effects of cancer
that are not caused by the tumor and its metastasis, or by infection, ischemia or metabolic …