Diabetic retinopathy: seeing beyond glucose-induced microvascular disease

DA Antonetti, AJ Barber, SK Bronson, WM Freeman… - Diabetes, 2006 - Am Diabetes Assoc
Diabetic retinopathy remains a frightening prospect to patients and frustrates physicians.
Destruction of damaged retina by photocoagulation remains the primary treatment nearly 50 …

[图书][B] Müller cells in the healthy and diseased retina

A Reichenbach, A Bringmann - 2010 - books.google.com
Müller glial cells ensheath all retinal neurons in vertebrate retinae. There are a multitude of
functional interactions between neurons and Müller cells, including delivery of the light …

Therapeutic targeting of diabetic retinal neuropathy as a strategy in preventing diabetic retinopathy

G de Moraes, CJ Layton - Clinical & Experimental …, 2016 - Wiley Online Library
Diabetes causes a panretinal neurodegeneration herein termed diabetic retinal neuropathy,
which manifests in the retina early and progresses throughout the disease. Clinical …

Whole genome assessment of the retinal response to diabetes reveals a progressive neurovascular inflammatory response

RM Brucklacher, KM Patel, HD VanGuilder… - BMC medical …, 2008 - Springer
Background Despite advances in the understanding of diabetic retinopathy, the nature and
time course of molecular changes in the retina with diabetes are incompletely described …

Rodent hyperglycemia-induced inner retinal deficits are mirrored in human diabetes

MT Pardue, CS Barnes, MK Kim… - … vision science & …, 2014 - tvst.arvojournals.org
Purpose:: To evaluate the utility of low luminance stimuli to functionally probe inner retinal
rod pathways in the context of diabetes mellitus in both rat and human subjects. Methods …

[HTML][HTML] An electrophysiological study of retinal function in the diabetic female rat

DJ Ramsey, H Ripps, H Qian - Investigative ophthalmology & …, 2006 - arvojournals.org
purpose. To examine retinal function in female Long-Evans rats with streptozotocin (STZ)-
induced diabetes. methods. Hyperglycemia was induced by IV injection of STZ, and ERG …

Upregulation of Glutamate–Aspartate Transporter by Glial Cell Line–Derived Neurotrophic Factor Ameliorates Cell Apoptosis in Neural Retina in Streptozotocin …

L Wang, QQ Deng, XH Wu, J Yu… - CNS neuroscience & …, 2013 - Wiley Online Library
Aims Dysfunction of glutamate uptake, largely mediated by the glutamate–aspartate
transporter (GLAST), may lead to retinal cell apoptosis in diabetic retinopathy. The aim of …

Effect of estrogen on electroretinographic responses in streptozotocin-induced diabetic female rats

H Yamashita, K Sugihara, C Yamada, S Tsutsumi… - Experimental eye …, 2010 - Elsevier
The aim of this study is to investigate the effects of estrogen on functional changes in the
retinas of streptozotocin (STZ)-induced diabetic rats by using an electroretinography …

The effect of topical anesthesia on the rat electroretinogram

S Sandalon, R Ofri - Documenta ophthalmologica, 2009 - Springer
Topical anesthetics are recommended when electroretinograms (ERGs) are recorded using
contact lens electrodes. However, these drugs act by blocking voltage-gated Na+ channels …

[引用][C] Müller 细胞与糖尿病视网膜病变

曾凯宏, 糜漫天, 许红霞 - 国际内分泌代谢杂志, 2007