The role of myeloperoxidase in biomolecule modification, chronic inflammation, and disease

MJ Davies, CL Hawkins - Antioxidants & redox signaling, 2020 - liebertpub.com
Significance: The release of myeloperoxidase (MPO) by activated leukocytes is critical in
innate immune responses. MPO produces hypochlorous acid (HOCl) and other strong …

Mammalian heme peroxidases: from molecular mechanisms to health implications

MJ Davies, CL Hawkins, DI Pattison… - Antioxidants & redox …, 2008 - liebertpub.com
A marked increase in interest has occurred over the last few years in the role that
mammalian heme peroxidase enzymes, primarily myeloperoxidase, eosinophil peroxidase …

[图书][B] Handbook Of Porphyrin Science: With Applications To Chemistry, Physics, Materials Science, Engineering, Biology And Medicine (Volumes 6-10)

KM Kadish, R Guilard, KM Smith - 2010 - books.google.com
This is the second set of Handbook of Porphyrin Science. Porphyrins, phthalocyanines and
their numerous analogues and derivatives are materials of tremendous importance in …

Myeloperoxidase-derived oxidation: mechanisms of biological damage and its prevention

MJ Davies - Journal of clinical biochemistry and nutrition, 2010 - jstage.jst.go.jp
抄録 There is considerable interest in the role that mammalian heme peroxidase enzymes,
primarily myeloperoxidase, eosinophil peroxidase and lactoperoxidase, may play in a wide …

[HTML][HTML] Independent evolution of four heme peroxidase superfamilies

M Zámocký, S Hofbauer, I Schaffner… - Archives of biochemistry …, 2015 - Elsevier
Four heme peroxidase superfamilies (peroxidase–catalase, peroxidase–cyclooxygenase,
peroxidase–chlorite dismutase and peroxidase–peroxygenase superfamily) arose …

Myeloperoxidase in human neutrophil host defence

WM Nauseef - Cellular microbiology, 2014 - Wiley Online Library
Human neutrophils represent the predominant leucocyte in circulation and the first
responder to infection. Concurrent with ingestion of microorganisms, neutrophils activate …

Redox properties of heme peroxidases

G Battistuzzi, M Bellei, CA Bortolotti, M Sola - Archives of biochemistry and …, 2010 - Elsevier
Peroxidases are heme enzymes found in bacteria, fungi, plants and animals, which exploit
the reduction of hydrogen peroxide to catalyze a number of oxidative reactions, involving a …

Second‐coordination sphere effects on selectivity and specificity of heme and nonheme iron enzymes

SP de Visser - Chemistry–A European Journal, 2020 - Wiley Online Library
Mononuclear iron‐containing enzymes are highly versatile oxidants that often react
stereospecifically and/or regioselectively with substrates. Combined experimental and …

Mode of action of lactoperoxidase as related to its antimicrobial activity: a review

F Bafort, O Parisi, JP Perraudin, MH Jijakli - Enzyme research, 2014 - Wiley Online Library
Lactoperoxidase is a member of the family of the mammalian heme peroxidases which have
a broad spectrum of activity. Their best known effect is their antimicrobial activity that …

Structural perspective on enzymatic halogenation

LC Blasiak, CL Drennan - Accounts of chemical research, 2009 - ACS Publications
Simple halogen substituents frequently afford key structural features that account for the
potency and selectivity of natural products, including antibiotics and hormones. For example …